TY - JOUR
TI - Discrimination of hip fractures by quantitative ultrasound of the
phalanges and the calcaneus and dual X-ray absorptiometry
AU - Damilakis, J
AU - Papadokostakis, G
AU - Pertsinakis, K
AU - Maris, T and
AU - Dimitriou, P
AU - Hadjipavlou, A
AU - Gourtsoyiannis, N
JO - European Journal of Radiology
PY - 2004
VL - 50
TODO - 3
SP - 268-272
PB - ELSEVIER SCI IRELAND LTD
SN - 0720-048X
TODO - 10.1016/j.ejrad.2004.01.023
TODO - osteoporosis; hip fractures; QUS; DXA
TODO - The aim of the current study was to evaluate the ability of different
techniques used for the assessment of bone status to discriminate
between postmenopausal women with and without hip fracture. Fifty-one
postmenopausal women (mean age 64.5 +/- 6.5) who had sustained a low
energy hip fracture and 51 age-matched controls (mean age 64.6 +/- 6.0)
were studied. Quantitative ultrasound (QUIS) assessment was carried out
using the Ubis 3000 device capable of measuring broadband ultrasound
attenuation (BUA) and speed of sound at the calcaneus (SOSC) and the
Sunlight Omnisense device capable of estimating speed of sound at the
phalanges (SOSp). Femoral neck bone mineral density (BMD) was assessed
using dual X-ray absorptiometry. Correlations between QUS variables
ranged from r = 0.35 to 0.72 and between QUS variables and BMD from r =
0.30 to 0.36. BMD was the best discriminator of hip fractures (odds
ratio = 3.61, area under Curve = 0.824). All QUS variables were
significant discriminators of hip fractures with odds ratios ranging
from 1.88 to 2.63 and areas under the ROC curves ranging from 0.663 to
0.740. Among the QUS variables, the SOSp showed the best odds ratio and
area under curve. Comparison between the areas under the ROC curve did
not show any significant difference between SOSp, BUA and BMD. On the
contrary, the difference between SOSC and BMD was significant (P <
0.05). In conclusion, BMD and QUS variables investigated in the current
study were significant discriminators of hip fractures. The
differentiation of the hip fractures by BMD was significantly better
than that of BUA measured at the calcaneus. Moreover, BMD discriminated
fractured patients better than BUA and SOSp, although the difference did
not reach statistical significance. (C) 2004 Elsevier Ireland Ltd. All
rights reserved.
ER -