TY - JOUR
TI - Perioperative anti-infective prophylaxis with teicoplanin compared to
cephalosporins in orthopaedic and vascular surgery involving prosthetic
material
AU - Vardakas, KZ
AU - Soteriades, ES
AU - Chrysanthopoulou, SA and
AU - Papagelopoulos, PJ
AU - Falagas, ME
JO - Clinical Microbiology and Infection
PY - 2005
VL - 11
TODO - 10
SP - 775-777
PB - WILEY-BLACKWELL PUBLISHING, INC
SN - 1198-743X
TODO - 10.1111/j.1469-0691.2005.01177.x
TODO - cephalosporins; orthopaedic surgery; prophylaxis; teicoplanin;
vancomycin; vascular surgery
TODO - A meta-analysis of randomised controlled trials evaluated the
effectiveness and safety of teicoplanin compared to first- or
second-generation cephalosporins for perioperative anti-infective
prophylaxis in orthopaedic and vascular surgery involving prosthetic
material. No differences were found between teicoplanin and
cephalosporins with respect to the development of infection at the site
of surgery or in remote areas of the body. In addition, there were no
significant differences in reported adverse effects or mortality. These
findings indicate that both regimens are equally effective in preventing
post-operative infections in orthopaedic and vascular surgery involving
prosthetic materials.
ER -