TY - JOUR
TI - Cutaneous and sensory effects of feminine hygiene pads among women with
recent genital infection
AU - Farage, MA
AU - Meyer, SJ
AU - Katsarou, A
AU - Bowtell, P and
AU - Deliveliotou, A
AU - Creatsas, G
JO - Cutaneous and Ocular Toxicology (formerly Journal of Toxicology - Cutaneous and Ocular Toxicology)
PY - 2006
VL - 25
TODO - 2
SP - 121-130
PB - Taylor and Francis Inc.
SN - 1556-9527, 1556-9535
TODO - 10.1080/15569520600695561
TODO - cutaneous effects; erythema; genital infection; irritation; menstrual;
prospective trial; sanitary pad; sensory effects; subjective effects;
susceptible population
TODO - We compared the skin compatibility of two menstrual pad technologies in
a single-center, parallel, randomized, examiner-blinded study involving
adult women. This report presents the results of a subset of 10
participants who had a genital infection within 12 months prior to the
start of the study. In a blinded fashion, participants were randomized
to receive one of the two pads for use over two menstrual periods.
Participants’ skin erythema was graded 24-48 hours following cessation
of menstrual flow and on day 14 of each menstrual cycle. Participants
subjectively reported any sensory effects. Vulvar erythema scores for
the mons pubis, labia majora, labia minora, perineum, buttocks, left
medial thigh, and right medial thigh assessed after both menstrual
cycles were not statistically different between groups or between the
two different products. A low incidence of itching and burning occurred
in both groups without statistical significance, none of the
participants experienced a recurrent or new genital infection. These
preliminary results show that participants with recent genital
infections included in clinical studies do not exhibit greater valvar
erythema or sensory effects than participants without recent genital
infection. The study showed that the safety profile of the products
tested remained acceptable in women with recent genital infection.
ER -