TY - JOUR TI - Dietary patterns and 10-year (2002-2012) incidence of type 2 diabetes: Results from the ATTICA cohort study AU - Koloverou, E. AU - Panagiotakos, D.B. AU - Georgousopoulou, E.N. AU - Grekas, A. AU - Christou, A. AU - Chatzigeorgiou, M. AU - Chrysohoou, C. AU - Tousoulis, D. AU - Stefanadis, C. AU - Pitsavos, C. AU - ATTICA Study Group AU - Skoumas, Y. AU - Katinioti, N. AU - Papadimitriou, L. AU - Masoura, C. AU - Vellas, S. AU - Lentzas, Y. AU - Kambaxis, M. AU - Palliou, K. AU - Metaxa, V. AU - Ntzouvani, A. AU - Mpougatsas, D. AU - Skourlis, N. AU - Papanikolaou, C. AU - Kouli, G.-M. AU - Christou, A. AU - Zana, A. AU - Ntertimani, M. AU - Kalogeropoulou, A. AU - Pitaraki, E. AU - Laskaris, A. AU - Hatzigeorgiou, M. AU - Grekas, A. AU - Vassiliadou, C. AU - Dedoussis, G. AU - Toutouza-Giotsa, M. AU - Tselika, C. AU - Poulopoulou, S. AU - Toutouza, M. JO - The Review of Diabetic Studies : RDS PY - 2016 VL - 13 TODO - 4 SP - 246-256 PB - SBDR - Society for Biomedical Diabetes Research SN - 1613-6071, 1614-0575 TODO - 10.1900/RDS.2016.13.246 TODO - adult; aged; anthropometry; Article; body height; body weight; cohort analysis; female; follow up; hip circumference; human; incidence; lifestyle; macronutrient; male; non insulin dependent diabetes mellitus; nutritional assessment; questionnaire; waist circumference; adverse effects; age; Diabetes Mellitus, Type 2; diet; ethnology; factor analysis; feeding behavior; Greece; healthy diet; middle aged; nutrition; patient compliance; Prediabetic State; prospective study; risk factor; urban health, Adult; Age Factors; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Factor Analysis, Statistical; Feeding Behavior; Female; Follow-Up Studies; Greece; Healthy Diet; Humans; Incidence; Male; Middle Aged; Nutrition Surveys; Patient Compliance; Prediabetic State; Prospective Studies; Risk Factors; Urban Health TODO - AIM: To identify dietary patterns among apparently healthy individuals and to determine their long-term effect on diabetes incidence. METHODS: During 2001-2002, a random sample of 3,042 men and women (18-89 years old), living in greater Athens, was randomly selected to participate in the study. During 2011-2012, the 10-year follow-up was performed in 2,583 participants (15% drop-out rate). After excluding participants with diabetes at baseline and those for whom no information on diabetes status was available at follow- up, the working sample consisted of 1,485 participants. Dietary habits were assessed by means of a validated semiquantitative, food frequency questionnaire. Factor analysis was performed to extract dietary patterns from 18 food groups. RESULTS: Diabetes diagnosis at follow-up was made in 191 participants, yielding an incidence rate of 12.9%. Six factors (i.e. dietary patterns) were identified that explained 54% of the variation in consumption. After adjusting for major confounders, and stratification by age-group, logistic regression revealed that the most healthful pattern consisted of the consumption of fruits, vegetables, legumes, bread, rusk, and pasta which reduced the 10-year diabetes risk by 40%, among participants aged 45-55 years. The association reached marginal statistical significance (95% CI: 0.34, 1.07), while no significant association was observed for the other age-groups. When the analysis was additionally adjusted for carbohydrate percentage, statistical significance was lost completely, suggesting a possibly mediating effect of this macronutrient. CONCLUSIONS: The results confirm the potentially protective effect of a plant-based dietary pattern in the primary prevention of diabetes, in particular among middle-aged people. Carbohydrate content may be a specific factor in this relationship; other micronutrients found in plant-based food groups may also play a role. © by Lab & Life Press/SBDR. ER -