TY - JOUR
TI - Optical coherence tomography biomarkers as predictive factors for postoperative visual acuity in patients with epiretinal membrane treated with vitrectomy
AU - Chatziralli, I.
AU - Dimitriou, E.
AU - Xirou, T.
AU - Kabanarou, S.A.
AU - Theodossiadis, G.
AU - Theodossiadis, P.
JO - Oman Journal of Ophthalmology
PY - 2020
VL - 13
TODO - 3
SP - 136-140
PB - Wolters Kluwer--Medknow Publications
SN - 0974-620X, 0974-7842
TODO - 10.4103/ojo.OJO_79_2020
TODO - triamcinolone, age;  aged;  Article;  best corrected visual acuity;  central retinal thickness;  clinical article;  controlled study;  data analysis software;  decision making;  demography;  epiretinal membrane;  female;  gender;  human;  male;  optical coherence tomography;  pars plana vitrectomy;  postoperative period;  preoperative evaluation;  retinal outer nuclear layer;  retinal thickness;  retrospective study;  spectral domain optical coherence tomography;  subretinal fluid;  treatment outcome;  visual acuity
TODO - BACKGROUND: The purpose of this retrospective study was to evaluate potential predictive factors of postoperative visual outcome in patients with idiopathic epiretinal membrane (iERM), treated with pars plana vitrectomy (PPV). METHODS: Participants in the study were 46 patients diagnosed with iERM, who underwent PPV. Best-corrected visual acuity measurement and spectral domain-optical coherence tomography (OCT) were performed at baseline (preoperatively), and at months 6 and 12 postoperatively. Demographic characteristics and OCT parameters were assessed as potential predictive factors for postoperative visual outcome. RESULTS: Increasing age, retinal thickness, presence of disorganization of inner retinal layers, ellipsoid zone disruption, and presence of vitreomacular traction were found to be negatively associated with postoperative visual acuity. Gender, presence of subretinal fluid, cysts in the inner or outer nuclear layer, and hyperreflective foci were not found to affect visual acuity. There was statistically significant improvement in visual acuity and central retinal thickness between baseline and months 6 and 12 in the study sample. CONCLUSIONS: It is important to determine predictive factors for visual outcome, so as to inform patients about prognosis and help in the decision-making of patients' management. © 2020 Wolters Kluwer Medknow Publications. All rights reserved.
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