TY - JOUR
TI - Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group
AU - Velissaris, D.
AU - Dimopoulos, G.
AU - Parissis, J.
AU - Alexiou, Z.
AU - Antonakos, N.
AU - Babalis, D.
AU - Gerakari, S.
AU - Kaldis, V.
AU - Koutoukas, P.
AU - Lada, M.
AU - Leventogiannis, K.
AU - Pantazopoulos, I.
AU - Papadopoulos, A.
AU - Polyzogopoulou, E.
AU - Gogos, C.
AU - Armaganidis, A.
AU - Giamarellos-Bourboulis, E.J.
JO - Infectious Diseases and Therapy
PY - 2020
VL - 9
TODO - 3
SP - 407-416
PB - Adis
SN - 2193-8229, 2193-6382
TODO - 10.1007/s40121-020-00301-w
TODO - plasminogen;  tumor necrosis factor;  urokinase;  urokinase receptor, algorithm;  angiogenesis;  APACHE;  artificial ventilation;  cell proliferation;  chronic kidney failure;  coronary angiography;  disease severity;  e-mail;  emergency ward;  extracorporeal oxygenation;  genotype;  glomerulosclerosis;  glomerulus filtration rate;  hospital mortality;  human;  intensive care unit;  length of stay;  leukocyte count;  multiple organ failure;  Note;  practice guideline;  priority journal;  prostate cancer;  proteinuria;  rheumatoid arthritis;  risk assessment;  septic shock;  Sequential Organ Failure Assessment Score
TODO - In light of the accumulating evidence on the negative predictive value of soluble urokinase plasminogen activator receptor (suPAR), a group of experts from the fields of intensive care medicine, emergency medicine, internal medicine and infectious diseases frame a position statement on the role of suPAR in the screening of patients admitted to the emergency department. The statement is framed taking into consideration existing publications and our own research experience. The main content of this statement is that sUPAR is a non-specific marker associated with a high negative predictive value for unfavourable outcomes; levels < 4 ng/ml indicate that it is safe to discharge the patient, whereas levels > 6 ng/ml are an alarming sign of risk for unfavourable outcomes. However, the suPAR levels should always be interpreted in light of the patient's history. © 2020, The Author(s).
ER -