TY - JOUR
TI - Giant intracranial congenital hemangiopericytoma/solitary fibrous tumor: A case report and literature review
AU - Giakoumettis, D.
AU - Nikas, I.
AU - Stefanaki, K.
AU - Kattamis, A.
AU - Sfakianos, G.
AU - Themistocleous, M.S.
JO - Surgical Neurology International
PY - 2019
VL - 10
TODO - 75
SP - 1-7
PB - SCIENTIFIC SCHOLAR LLC
SN - null
TODO - 10.25259/SNI-85-2019
TODO - brain derived neurotrophic factor receptor;  cyclophosphamide;  dactinomycin;  transcription factor Ets;  vincristine, anterior fontanel;  apoptosis;  bleeding tendency;  brain ventricle peritoneum shunt;  cancer combination chemotherapy;  case report;  cavernous sinus;  cell density;  child;  clinical article;  computer assisted tomography;  congenital tumor;  craniotomy;  echography;  female;  follow up;  frontal lobe;  giant intracranial congenital hemangiopericytoma;  giant intracranial congenital hemangiopericytoma;  head circumference;  hemangiopericytoma;  histopathology;  human;  intracranial tumor;  jaundice;  medical history;  meninx;  microsurgery;  middle cranial fossa;  mitosis rate;  multiple cycle treatment;  muscle hypotonia;  muscle tone;  neonatal intensive care unit;  nerve paralysis;  neuroimaging;  neurologic disease;  neurosurgery;  nuclear magnetic resonance imaging;  obstructive hydrocephalus;  ophthalmoplegia;  parietal lobe;  patient referral;  posterior fossa;  postoperative care;  postoperative period;  priority journal;  reverse transcription polymerase chain reaction;  Review;  school child;  solitary fibrous tumor;  staining;  temporal lobe
TODO - Background: Hemangiopericytoma and solitary fibrous tumor (HPC/SFT) are considered to be one category according to the WHO 2016 classification of central nervous system tumors. HPC/SFT are subdivided into infantile (congenital) and adult type. Both are extremely rare entities, with little knowledge about etiology, prognosis, and optimal therapeutic strategy. Case Description: A 10-day-old girl was referred to our neurosurgical department due to hypotonia, palsy of the right oculomotor nerve, and prominent frontal fontanel. Imaging studies revealed a large occupying mass in the right middle cerebral fossa and the suprasellar cisterns. Only a subtotal resection of the tumor was possible, and postoperatively, she underwent chemotherapy (CHx). After a 3-year follow-up, the girl has minimum neurologic signs and receives no medications, and she can walk when she is supported. Conclusion: Congenital HPC/SFT is considered to have a benign behavior with a good prognosis. Treatment with gross total resection, when it is feasible, is the key to a good prognosis and low rates of recurrence. However, there is no consensus on the therapeutic strategy of a HPC/SFT, which is difficult to be completely resected. Literature lacks a therapeutic algorithm for these tumors, and thus, more clinical studies are needed to reach a consensus. ©2019 Published by Scientific Scholar on behalf of Surgical Neurology International.
ER -