TY - JOUR TI - The Micro-Elimination Approach to Eliminating Hepatitis C: Strategic and Operational Considerations AU - Lazarus, J.V. AU - Safreed-Harmon, K. AU - Thursz, M.R. AU - Dillon, J.F. AU - El-Sayed, M.H. AU - Elsharkawy, A.M. AU - Hatzakis, A. AU - Jadoul, M. AU - Prestileo, T. AU - Razavi, H. AU - Rockstroh, J.K. AU - Wiktor, S.Z. AU - Colombo, M. JO - Seminars in Liver Disease PY - 2018 VL - 38 TODO - 3 SP - 181-192 PB - Thieme Medical Publishers Inc SN - 0272-8087, 1098-8971 TODO - 10.1055/s-0038-1666841 TODO - disease elimination; graft recipient; hematologic disease; hemodialysis patient; hemophilia; hepatitis C; high risk population; human; Human immunodeficiency virus infection; indigenous people; migrant; mixed infection; people who inject drug; prevalence; priority journal; prisoner; Review; cooperation; disease eradication; ethnology; global health; health care policy; hepatitis C; integrated health care system; interdisciplinary communication; international cooperation; legislation and jurisprudence; management; nonbiological model; organization and management; risk factor; stakeholder engagement; transmission; vulnerable population, antivirus agent, Antiviral Agents; Cooperative Behavior; Delivery of Health Care, Integrated; Disease Eradication; Global Health; Health Policy; Hepatitis C; Humans; Interdisciplinary Communication; International Cooperation; Models, Organizational; Policy Making; Prevalence; Risk Factors; Stakeholder Participation; Vulnerable Populations TODO - The introduction of efficacious new hepatitis C virus (HCV) treatments galvanized the World Health Organization to define ambitious targets for eliminating HCV as a public health threat by 2030. Formidable obstacles to reaching this goal can best be overcome through a micro-elimination approach, which entails pursuing elimination goals in discrete populations through multi-stakeholder initiatives that tailor interventions to the needs of these populations. Micro-elimination is less daunting, less complex, and less costly than full-scale, country-level initiatives to eliminate HCV, and it can build momentum by producing small victories that inspire more ambitious efforts. The micro-elimination approach encourages stakeholders who are most knowledgeable about specific populations to engage with each other and also promotes the uptake of new models of care. Examples of micro-elimination target populations include medical patients, people who inject drugs, migrants, and prisoners, although candidate populations can be expected to vary greatly in different countries and subnational areas. © 2018 by Thieme Medical Publishers, Inc. ER -