TY - JOUR TI - Patient-and Caregiver-Related Factors Associated with Caregiver Assessed Global Deterioration Scale Scoring in Demented Patients AU - Mougias, A.A. AU - Christidi, F. AU - Kontogianni, E. AU - Skaltsounaki, E. AU - Politis, A. AU - Politis, A. JO - Current Gerontology and Geriatrics Research PY - 2018 VL - 2018 TODO - null SP - null PB - Hindawi Limited SN - 1687-7063, 1687-7071 TODO - 10.1155/2018/9396160 TODO - null TODO - Background. Informant-based rating scales are widely used in dementia but patients' and caregivers' features influence the final scoring. We aimed to evaluate the role of patient-and caregiver-related factors in a caregiver rated Global Deterioration Scale (GDS) score in a sample of Greek patients with dementia. Methods. We included 194 patients with dementia and 194 caregivers/family relatives; Mini-Mental State Examination (MMSE); Neuropsychiatric Inventory (NPI); Katz Index of Activities of Daily Living (K-IADL) were administered to (a) patients and Center for Epidemiologic Studies-Depression (CES-D) Scale; Zarit Burden Interview (ZBI) to (b) caregivers. Participants' demographics and patients' and caregivers' characteristics were entered into a 3-block regression analysis. Results. The final model explained 55% of the total variance of the caregiver assessed GDS score. The following variables significantly contributed to the final model: MMSE (β=-0.524); K-IADL (β=-0.264); ZBI (β=0.145). Conclusion. We herein confirm the contribution of patients' cognitive and functional status and caregivers' burden in caregiver rated GDS scoring irrespective of demographic-related characteristics. © 2018 Antonios A. Mougias et al. ER -