TY - JOUR
TI - Breast cancer incidence in Greek women in relation to ABO blood groups and Rh factor
AU - Stamatakos, M.
AU - Kontzoglou, K.
AU - Safioleas, P.
AU - Safioleas, C.
AU - Manti, C.
AU - Safioleas, M.
JO - International Seminars in Surgical Oncology
PY - 2009
VL - 6
TODO - null
SP - 14
PB - 
SN - 1477-7800
TODO - 10.1186/1477-7800-6-14
TODO - rhesus antigen, adult;  aged;  article;  blood group A;  blood group ABO system;  breast cancer;  cancer incidence;  cancer patient;  clinical feature;  controlled study;  correlation analysis;  demography;  distant metastasis;  family history;  female;  follow up;  Greece;  histology;  human;  immunohistochemistry;  intraductal carcinoma;  laboratory test;  lymph node metastasis;  major clinical study;  mastectomy;  prognosis;  risk assessment;  risk factor
TODO - Aim: To investigate the correlation between breast cancer in Greek women and ABO blood groups. Material-methods: In 166 female patients with breast cancer factors such as blood group, histological type, family history, presence or absence of nodal and/or distant metastases were examined. These patients had similar demographic, clinical, surgical, immunohistochemical, laboratory, and follow-up data and this group is representative of general population of women in Greece. Results: The ductal type of breast cancer was differentially distributed in blood groups Rh (+) (P ≤ 0.001). In patients with A (+) blood group the ductal type of breast cancer was present in 49.6% of cases, in relation to the other blood groups and in AB blood group the same type occurred rarely (3.6%). Rh (+) women with positive family history were more often found in A blood group. The relative risk of metastasis in Rh (-) patients was 4.2 times higher than that in Rh (+) patients. Among Rh (+) patients, the relative risk of metastasis was 1.29 times higher in A blood group than in other blood groups. Conclusion: Blood group A is often associated with ductal breast cancer (49.6%), in contrast to the other blood groups and particularly to blood group AB (3.6%). Blood group A and, particularly, A (-) has the worst prognosis of all. © 2009 Stamatakos et al; licensee BioMed Central Ltd.
ER -