TY - JOUR
TI - Diagnostic problems in severe neonatal jaundice and G6PD deficiency in Greece
AU - Zannos-Mariolea, L.
AU - Thomaidis, Th.
AU - Georgizas, G.
AU - Gavrielidou, E.
AU - Benetos, S.
JO - Archives of Disease in Childhood
PY - 1968
VL - 43
TODO - 227
SP - 36-41
PB - BMJ Publishing Group
SN - 0003-9888, 1468-2044
TODO - 10.1136/adc.43.227.36
TODO - diagnostic agent;  glucose 6 phosphate dehydrogenase;  glutathione;  methemoglobin, article;  comparative study;  erythrocyte;  female;  glucose 6 phosphate dehydrogenase deficiency;  Greece;  human;  male;  newborn;  newborn jaundice, Comparative Study;  Erythrocytes;  Female;  Glucosephosphate Dehydrogenase;  Glucosephosphate Dehydrogenase Deficiency;  Glutathione;  Greece;  Human;  Infant, Newborn;  Jaundice, Neonatal;  Male;  Methemoglobin
TODO - Examinations were made of 302 full-term newborn infants with severe jaundice (indirect bilirubin >20 mg./100 ml. in 79.7% of the cases) for G6PD deficiency by 3 diagnostic methods, of which the methaemoglobin-elution test proved to be superior. 99 or 32.7% of the cases were found to be G6PD deficient by the latter method (59 males and 40 females): a male : female ratio of 1.47. 8 of the 59 males had normal values of G6PD activity and are probably cases of the mild G6PD deficiency type. The difficulties involved in the diagnosis of G6PD deficiency in the newborn period were discussed.
ER -