TY - JOUR
TI - Dose characterization of the new Bebig IsoSeed (R) I25.S17 using polymer
gel and MRI
AU - Pantelis, Evaggelos
AU - Baltas, Dimos
AU - Georgiou, Evaggelos and
AU - Karaiskose, Pantelis
AU - Lymperopoulou, Georgia
AU - Papagiannis,
AU - Panagiotis
AU - Sakelliou, Loukas
AU - Seimenis, Ioannis
AU - Stilliaris,
AU - Efstathios
JO - NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION
A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
PY - 2006
VL - 569
TODO - 2, SI
SP - 529-532
PB - ELSEVIER SCIENCE BV
SN - null
TODO - 10.1016/j.nima.2006.08.139
TODO - polymer gel; MRI; dosimetry; brachytherapy
TODO - A new, molybdenum core, I-125 interstitial brachytherapy seed is
marketed by Bebig GmbH (IsoSeed(R) 125.S17) and our group has performed
its Dosimetric characterization using Monte Carlo (MC) simulation and
Thermoluminescence dosimetry (TLD) as recommended by the AAPM TG-43U1
prior to the clinical implementation of new low-energy seeds. This work
presents the results of a supplementary experimental dosimetry study
performed using PABIG polymer gel and Magnetic Resonance Imaging (MRI).
One new I25.S17 seed and a commercially available, gold core. Bebig
IsoSeed(R) I25.S06 I-125 seed were positioned at two different locations
in a vial filled with water equivalent, PABIG-polymer gel. The gel with
the sources in place was M R scanned in 31) at various time intervals
after seed placement using a time efficient, 3D, dual echo Turbo Spin
Echo pulse sequence. The consensus dosimetry parameters published in the
TG-43U1 for the I25.S06 seed were used to derive the gel response
calibration curve for each scanning session. The calibration data were
then used to provide dosimetry results for the new I25.S17 seed.
Experimental results for the new seed in the form of dose distributions
as well as dosimetric quantities in the prevalent TG-43 dosimetric
formalism were found to be in close agreement with corresponding MC and
TLD results. This finding suggests that the polymer gel-MRI method could
at least play a supplementary role to TLD dosimetry in the dose
characterization of low energy/low dose rate brachytherapy sources,
especially in view of its potential for measurements with a fine spatial
resolution down to short distances which are inhibitory to conventional
experimental techniques. (c) 2006 Elsevier B.V. All rights reserved.
ER -