TY - JOUR
TI - Psychosocial and Trauma-Related Stress and Risk of Dementia: A Meta-Analytic Systematic Review of Longitudinal Studies
AU - Bougea, A.
AU - Anagnostouli, M.
AU - Angelopoulou, E.
AU - Spanou, I.
AU - Chrousos, G.
JO - Journal of Geriatric Psychiatry and Neurology
PY - 2022
VL - 35
TODO - 1
SP - 24-37
PB - SAGE Publications Inc.
SN - 0891-9887, 1552-5708
TODO - 10.1177/0891988720973759
TODO - dementia;  exhaustion;  human;  ICD-9;  incidence;  job stress;  Maastricht Vital Exhaustion Questionnaire;  marriage;  mental stress;  meta analysis;  posttraumatic stress disorder;  prevalence;  prognosis;  questionnaire;  Review;  risk factor;  social status;  socioeconomics;  systematic review;  Alzheimer disease;  longitudinal study;  posttraumatic stress disorder, Alzheimer Disease;  Humans;  Longitudinal Studies;  Stress Disorders, Post-Traumatic;  Systematic Reviews as Topic
TODO - Stress has deleterious effects on brain health and yet, the prognostic value of psychosocial stress regarding the most common types of dementias, including Alzheimer disease, is still unclear. The primary aim of this systematic review was to explore the association between psychosocial stress and late onset dementia. We classified 24articles from Medline, PsycINFO, CINAHL, and Web of Science, as pertaining toxic categories of psychosocial and trauma-related stress (low socio-economic status [SES] related inequalities, marital status, posttraumatic stress disorder, work stress, “vital exhaustion” [VE], and, combined stressors). Using the Quality of Prognosis Studies in Systematic Reviews tool, we judged the quality of evidence to be low. This systematic review provided some non-robust, yet suggestive evidence that the above psychosocial types of stress are associated with increased risk of dementia in later life. Future robust, longitudinal studies with repeated validated measures of psychosocial stress and dementiaare required to strengthen or refute these findings. © The Author(s) 2020.
ER -