TY - JOUR TI - Assessment of Anatomical and Functional Macular Changes with Optical Coherence Tomography Angiography After Macula-Off Rhegmatogenous Retinal Detachment Repair. AU - Christou, E.E. AU - Kalogeropoulos, C. AU - Georgalas, I. AU - Stavrakas, P. AU - Christodoulou, E. AU - Batsos, G. AU - Stefaniotou, M. JO - Seminars in Ophthalmology PY - 2021 VL - 36 TODO - 3 SP - 119-127 PB - Taylor and Francis Ltd. SN - 0882-0538, 1744-5205 TODO - 10.1080/08820538.2021.1889618 TODO - adult; article; blood vessel density; capillary; case control study; clinical article; controlled study; female; human; male; optical coherence tomography angiography; pars plana vitrectomy; retina detachment surgery; retina macula lutea; retrospective study; diagnostic imaging; fluorescence angiography; optical coherence tomography; retina blood vessel; retina detachment; visual acuity; vitrectomy, Case-Control Studies; Fluorescein Angiography; Humans; Macula Lutea; Retinal Detachment; Retinal Vessels; Retrospective Studies; Tomography, Optical Coherence; Visual Acuity; Vitrectomy TODO - Purpose: To evaluate macular capillary plexus changes with OCT-angiography with regard to macular detachment duration in macula-off rhegmatogenous retinal detachment (RRD). Methods: 23 eyes of 23 patients were included in this retrospective case–control study and were divided into 2 groups. Group-A had a macular detachment duration of 0 to 10 days and group-B of 11 to 30 days. All eyes underwent a single successful pars plana vitrectomy (PPV) and gas tamponade. We analysed the OCT-A characteristics and visual outcomes at 12 weeks postoperatively in the 2 groups. The fellow eye was used as control. Results: Vessel density (VD) and flow density (FD) in the superficial capillary plexus (SCP) were significantly lower in group-B (p < .01) than in group-A and control. FAZ SCP in both groups was significantly larger than the control (p < .01), although it did not differ significantly between the two groups (p = 1.000). BCVA was significantly lower in group-B compared to group-A (p < .01). BCVA was positively correlated with VD SCP in group B (p = .015), but not in group-A. Postoperative BCVA had no correlation with FAZ SCP in both groups. Conclusions: The macular detachment duration could be a predicting factor of flow density in macular capillary plexus which in turn might be an indicator of visual outcomes in chronic cases. © 2021 Taylor & Francis. ER -