TY - JOUR
TI - Nasal High Flow Use in COPD Patients with Hypercapnic Respiratory Failure: Treatment Algorithm & Review of the Literature
AU - Pantazopoulos, I.
AU - Daniil, Z.
AU - Moylan, M.
AU - Gourgoulianis, K.
AU - Chalkias, A.
AU - Zakynthinos, S.
AU - Ischaki, E.
JO - COPD: Journal of Chronic Obstructive Pulmonary Disease
PY - 2020
VL - 17
TODO - 1
SP - 101-111
PB - Taylor and Francis Ltd.
SN - 1541-2555, 1541-2563
TODO - 10.1080/15412555.2020.1715361
TODO - algorithm;  assisted ventilation;  chronic obstructive lung disease;  disease exacerbation;  human;  hypercapnia;  inhalational drug administration;  nasal high flow therapy;  priority journal;  respiratory failure;  Review;  algorithm;  cannula;  chronic obstructive lung disease;  hypercapnia;  noninvasive ventilation;  oxygen therapy;  pathophysiology;  procedures;  respiratory failure, Algorithms;  Cannula;  Humans;  Hypercapnia;  Noninvasive Ventilation;  Oxygen Inhalation Therapy;  Pulmonary Disease, Chronic Obstructive;  Respiratory Insufficiency
TODO - Nasal high flow (NHF) therapy has recently gained attention as a new respiratory support system and is increasingly being utilized in every day clinical practice. Recent studies suggest that it may also be effective in patients with hypercapnia and suggest NHF as a possible alternative for patients who cannot tolerate standard noninvasive ventilation. The present review discusses the mechanisms of action that make NHF potentially suitable for chronic obstructive pulmonary disease (COPD) patients and evaluates the current evidence of NHF use for treatment of stable hypercapnic COPD patients as well as acute hypercapnic exacerbation of COPD. An algorithm is also proposed for the clinical application of NHF in patients with acute hypercapnic exacerbation of COPD, based on current literature. © 2020, © 2020 Taylor & Francis Group, LLC.
ER -