TY - JOUR TI - Endoscopic drainage in patients with malignant extrahepatic biliary obstruction: When and how AU - Mangiavillano, B. AU - Papanikolaou, I.S. AU - Arvanitakis, M. AU - Auriemma, F. AU - Bianchetti, M. AU - Tarantino, I. AU - Traina, M. AU - Deviere, J. AU - Repici, A. JO - European Journal of Gastroenterology and Hepatology PY - 2020 VL - null TODO - null SP - 1279-1283 PB - Lippincott Williams and Wilkins SN - 0954-691X, 1473-5687 TODO - 10.1097/MEG.0000000000001752 TODO - adverse event; cholestasis; diagnostic imaging; endoscopic retrograde cholangiopancreatography; endoscopic sphincterotomy; human; obstructive jaundice; stent; treatment outcome, Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Cholestasis, Extrahepatic; Drainage; Humans; Sphincterotomy, Endoscopic; Stents; Treatment Outcome TODO - The question of when and how to drain a malignant biliary obstruction (MBO), both intrinsic or extrinsic, remains a controversial point among endoscopists. An important factor that influences the decision to drain an MBO or not is if the patient is a surgical candidate or not and, in the former case, if the patients must undergo neoadiuvant chemotherapy or not. Other questions arising during biliary drainage in MBO patients is which type of stent should be chosen, plastic or metal, and if endoscopic biliary sphincterotomy must be performed or not when a stent is placed. The present review attempts to answer these questions and summarizes the optimal approach toward patients with MBO based on the available evidence. © 2020 Thieme Medical Publishers, Inc.. All rights reserved. ER -