TY - JOUR
TI - A Unique Case of Primary Extranodal Marginal Zone Lymphoma of the Anal Canal
AU - Diamantopoulos, P.
AU - Dryllis, G.
AU - Tsourouflis, G.
AU - Petevi, K.
AU - Boutsikas, G.
AU - Rondogianni, P.
AU - Boutsis, D.
AU - Korkolopoulou, P.
AU - Konstantopoulos, K.
AU - Angelopoulou, M.K.
AU - Meletis, J.
AU - Kanellis, G.
AU - Vassilakopoulos, T.P.
JO - Acta Haematologica
PY - 2019
VL - 142
TODO - 2
SP - 87-91
PB - S Karger AG
SN - 0001-5792, 1421-9662
TODO - 10.1159/000495601
TODO - chlorambucil;  fluorodeoxyglucose f 18;  immunoglobulin lambda chain;  rituximab, adult;  anal canal;  Article;  case report;  clinical article;  colonoscopy;  constipation;  gastrointestinal endoscopy;  histology;  human;  lymphocytic infiltration;  male;  marginal zone lymphoma;  middle aged;  multiple cycle treatment;  positron emission tomography-computed tomography;  priority journal;  remission;  anus tumor;  immunology;  marginal zone lymphoma;  metabolism;  microbiology;  pathology, Anus Neoplasms;  Humans;  Lymphoma, B-Cell, Marginal Zone;  Male;  Middle Aged
TODO - Marginal zone lymphomas represent approximately 10-12% of all B-cell lymphomas. Extranodal marginal zone lymphomas (EMZL) or mucosa-associated lymphoid tissue (MALT) lymphomas are the most common subtype. Almost half of all MALT lymphomas arise in the gastrointestinal (GI) tract and, while the stomach is the most common site of GI involvement, the small and large intestines can also be involved. Rare cases of MALT lymphoma involving the rectum have been reported; however, to our knowledge, involvement of the anal canal has never been reported in the literature. Here, we describe a unique case of MALT lymphoma of the anal canal. Infectious agents have been implicated in the pathogenesis of MALT lymphomas, possibly through persistent antigenic stimulation of the area; however, in our case no such infection was documented. © 2019 S. Karger AG, Basel. All rights reserved.
ER -