TY - JOUR
TI - Neonatal screening for congenital CMV infection stresses the importance of maternal nonprimary infection even in an area where prenatal serology testing is common
AU - Papaevangelou, V.
AU - Christoni, Z.
AU - Vliora, C.
AU - Kottaridi, C.
AU - Fotiou, A.
AU - Malamitsi-Puchner, A.
AU - Mentis, A.
AU - Karakitsos, P.
AU - Syggelou, A.
JO - Journal of Maternal-Fetal and Neonatal Medicine
PY - 2019
VL - 32
TODO - 11
SP - 1901-1904
PB - Taylor and Francis Ltd.
SN - 1476-7058, 1476-4954
TODO - 10.1080/14767058.2017.1416605
TODO - Cytomegalovirus antibody;  immunoglobulin G, adult;  Article;  asymptomatic infection;  cohort analysis;  congenital infection;  controlled study;  cytomegalovirus infection;  dried blood spot testing;  female;  human;  incidence;  major clinical study;  male;  newborn;  newborn screening;  perception deafness;  prenatal care;  priority journal;  serology;  asymptomatic infection;  case report;  cytomegalovirus infection;  Greece;  pregnancy;  prevalence, Adult;  Asymptomatic Infections;  Cohort Studies;  Cytomegalovirus Infections;  Female;  Greece;  Humans;  Infant, Newborn;  Pregnancy;  Prevalence
TODO - Aim and Methods: Dried blood spots from 2149 newborns were examined to diagnose congenital cytomegalovirus (cCMV). Results: Prenatal CMV-IgG antibodies had been measured during prenatal care in 1287 (60.3%) of mothers and 980 (76.1%) of them were found seropositive. cCMV incidence was 0.47%. All newborns were asymptomatic; 9/10 were born post nonprimary maternal infection; two developed sensorineural hearing loss. Conclusions: In a country where prenatal CMV testing is common and therefore a false sense of control might prevail, nonprimary maternal infection should not be overlooked. Indeed, women of childbearing age should be educated on CMV prevention measures irrespectively to their serostatus. © 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group.
ER -