TY - JOUR
TI - Optical Biometry Derived Axial Length Measurements Following Intravitreal Anti-Vascular Endothelial Growth Factor Treatment for Macular Edema
AU - Kymionis, G.D.
AU - Giarmoukakis, A.
AU - Apostolidi, I.K.
AU - Blazaki, S.V.
AU - Tsoulnaras, K.I.
AU - Moschandrea, J.
AU - Panagopoulou, S.
AU - Tsilimbaris, M.K.
JO - Seminars in Ophthalmology
PY - 2018
VL - 33
TODO - 4
SP - 488-491
PB - Taylor and Francis Ltd.
SN - 0882-0538, 1744-5205
TODO - 10.1080/08820538.2017.1303520
TODO - ranibizumab;  angiogenesis inhibitor;  ranibizumab;  vasculotropin A, aged;  Article;  biometry;  central retinal thickness;  clinical article;  comparative study;  controlled study;  eye axis length;  female;  follow up;  human;  macular edema;  male;  observational study;  priority journal;  prospective study;  spectral domain optical coherence tomography;  antagonists and inhibitors;  biometry;  diagnostic imaging;  eye axis length;  eye fundus;  fluorescence angiography;  intravitreal drug administration;  macular edema;  optical coherence tomography;  pathology;  pathophysiology;  procedures;  retina macula lutea;  visual acuity, Aged;  Angiogenesis Inhibitors;  Axial Length, Eye;  Biometry;  Female;  Fluorescein Angiography;  Fundus Oculi;  Humans;  Intravitreal Injections;  Macula Lutea;  Macular Edema;  Male;  Prospective Studies;  Ranibizumab;  Tomography, Optical Coherence;  Vascular Endothelial Growth Factor A;  Visual Acuity
TODO - Purpose: To evaluate axial length (AL) alterations in patients with macular disease over the course of intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment. Methods: In this prospective, comparative study, 33 patients with macular edema underwent unilaterally intravitreal anti-VEGF therapy and were followed for two months; the contralateral eyes were considered as controls. Central retinal thickness (CRT) was measured with spectral-domain optical coherence tomography and AL with an IOL-Master optical biometer. Results: CRT of the treated eyes decreased by 35.33 ± 65.59 μm (range, –222.00–67 μm), while AL increased by 0.008 ± 0.062 mm (range, –0.11–0.18 mm). CRT of the control group decreased by 9.82 ± 65.40 μm (range, –203–182 μm), and AL increased by 0.011 ± 0.129 mm (range, –0.20–0.67 mm). No significant correlation was detected between CRT and AL parameters (rhos=0.026, P=0.882). Conclusions: Anti-VEGF administration has no significant impact on optical biometry-derived AL measurements. © Taylor & Francis.
ER -