TY - JOUR
TI - An unusual case of diffuse Merkel cell carcinoma successfully treated with low dose radiotherapy
AU - Chatzinasiou, F.
AU - Papadavid, E.
AU - Korkolopoulou, P.
AU - Levidou, G.
AU - Panayiotides, I.
AU - Theodoropoulos, K.
AU - Pogka, V.
AU - Asimakopoulos, C.
AU - Rigopoulos, D.
JO - Dermatologic Therapy
PY - 2015
VL - 28
TODO - 5
SP - 282-286
PB - Blackwell Publishing Inc.
SN - 1396-0296, 1529-8019
TODO - 10.1111/dth.12238
TODO - CD56 antigen;  CD57 antigen;  chromogranin;  cytokeratin 18;  cytokeratin 20;  cytokeratin 8;  protein bcl 2;  synaptophysin;  transcription factor PAX5;  virus large T antigen, aged;  Article;  cancer radiotherapy;  case report;  female;  hip fracture;  histopathology;  human;  human tissue;  leg disease;  leg tumor;  Merkel cell polyomavirus;  Merkel cell tumor;  radiation dose;  skin defect;  skin tumor;  treatment response;  Carcinoma, Merkel Cell;  isolation and purification;  pathology;  Skin Neoplasms;  treatment outcome;  very elderly, Aged, 80 and over;  Carcinoma, Merkel Cell;  Female;  Humans;  Merkel cell polyomavirus;  Skin Neoplasms;  Treatment Outcome
TODO - Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine carcinoma of the skin. MCC should be included in the diagnosis of a rapidly growing infiltrating mass and histology as well as laboratory investigations such as Merkel cell polyoma virus (MCPyV) detection are valuable in its diagnosis. We present an unusual case of giant MCC-positive MCPyV in a Greek woman located on the lower leg. Our patient is very unusual in terms of her extensive MCC and her rapid and complete response to radiotherapy. © 2015 Wiley Periodicals, Inc.
ER -