TY - JOUR
TI - Assessment of the psychometric properties of the EQ-5D-3L and EQ-5D-5L instruments in psoriasis
AU - Yfantopoulos, J.
AU - Chantzaras, A.
AU - Kontodimas, S.
JO - Archives of Dermatological Research. Archiv fόr Dermatologische Forschung
PY - 2017
VL - 309
TODO - 5
SP - 357-370
PB - Springer-Verlag
SN - 0340-3696, 1432-069X
TODO - 10.1007/s00403-017-1743-2
TODO - adult;  aged;  anxiety;  Article;  body mass;  clinical study;  depression;  Dermatology Life Quality Index;  discriminant validity;  female;  health status;  human;  intermethod comparison;  major clinical study;  male;  multicenter study;  priority journal;  prospective study;  psoriasis;  psoriasis vulgaris;  psychometry;  quality of life;  self care;  skin disease assessment;  visual analog scale;  adolescent;  analogs and derivatives;  classification;  clinical trial;  comparative study;  health survey;  middle aged;  outcome assessment;  procedures;  psoriasis;  psychology;  psychometry;  young adult, betamethasone;  betamethasone-17,21-dipropionate;  calcipotriol;  calcitriol;  dermatological agent, Adolescent;  Adult;  Aged;  Anxiety;  Betamethasone;  Calcitriol;  Depression;  Dermatologic Agents;  Female;  Health Status;  Health Surveys;  Humans;  Male;  Middle Aged;  Outcome Assessment (Health Care);  Prospective Studies;  Psoriasis;  Psychometrics;  Quality of Life;  Young Adult
TODO - The aim of this study was to assess the psychometric properties of the five-level (EQ-5D-5L) in comparison with the standard three-level (EQ-5D-3L) classification systems of the EQ-5D in a sample of psoriatic patients. Psoriatic subjects (n = 396) recruited from 16 private practicing centers from various areas of Greece self-completed the two EQ-5D versions and the Dermatology Life Quality Index, while information was also collected on socio-demographics, clinical characteristics and comorbidities. The EQ-5D-5L and EQ-5D-3L were evaluated in terms of agreement, feasibility, ceiling effects, redistribution properties, inconsistency, informativity, and convergent and known-groups validity. Missing values were negligible in both versions. The agreement between the EQ-5D-5L and the EQ-5D-3L was very high (ICC = 0.94), while the largest differences were identified for subjects with moderate health status. Ceiling effects decreased in the EQ-5D-5L system by 14.08% (p < 0.05), with “anxiety/depression” showing the highest relative reduction (−10.31%; p < 0.05). Overall inconsistency was rather low (1.7%) and respondents preferred to report milder problems in the EQ-5D-5L. Absolute informativity improved by 56.42% in the EQ-5D-5L, while relative informativity declined by 9.24%, with only “anxiety/depression” demonstrating a small increase (6.77%). Both instruments demonstrated good convergent and known-groups validity, with evidence of a slightly better convergent performance and discriminatory efficiency of the EQ-5D-5L. In conclusion, both instruments demonstrated consistency, valid redistribution and good construct validity. The EQ-5D-5L system may be preferable to the EQ-5D-3L in psoriatic patients, as it demonstrated a marginally better performance in terms of reduced ceiling effects, increased informativity, and improved convergent and known-groups validity efficiency, particularly in the domain of “anxiety/depression”. © 2017, Springer-Verlag Berlin Heidelberg.
ER -