TY - JOUR
TI - Effect of selenium and Ascaridia galli infection on antioxidant
biomarkers in broiler chickens: a mathematical model for parasite
reduction and host growth
AU - Gabrashanska, M.
AU - Galvez-Morros, M.
AU - Teodorova, S. E. and
AU - Ermidou-Pollet, S.
AU - Pollet, S.
JO - Journal of Helminthology
PY - 2007
VL - 81
TODO - 4
SP - 399-408
PB - Cambridge University Press
SN - 0022-149X, 1475-2697
TODO - 10.1017/S0022149X07868787
TODO - null
TODO - The activity of selenium-dependent glutathione peroxidase (GPX), liver
concentration of vitamin E, and plasma and liver selenium levels were
used for estimation of the antioxidant status of broiler chickens
infected with Ascaridia galli. These biomarkers were recorded in an
experiment covering 70 days p.i. At the same time the establishment rate
of A. galli in chicken intestines, gain in the host body weight and
chicken survival were studied. Broiler chickens (Cobb hybrids) were
infected with 1450 embryonated A. galli eggs and treated with Sel-plex.
A mathematical model was applied to determine the rate of nematode
reduction and the relative rate of gain of host body weight, which are
essential kinetic parameters of parasite-host interaction. The activity
of GPX increased with both elevated selenium and reduced infection
levels. The concentrations of selenium and vitamin E, and the GPX
activity in the infected chickens demonstrated a similar pattern of
change with time after day 30 p.i. The supplementation of the broilers
with dietary selenium in the form of Sel-plex improved their antioxidant
status. Increases by 29% in vitamin E concentration, 15% in GPX
activity, and 22% in liver selenium concentration, respectively, were
recorded in the infected and treated, compared to infected and untreated
broilers.
ER -