TY - JOUR TI - The use of Speckle Reduction Imaging (SRI) Ultrasound in the characterization of carotid artery plaques AU - Liasis, Nikolaos AU - Klonaris, Chris AU - Katsargyris, Athanasios and AU - Georgopoulos, Sotirios AU - Labropoulos, Nicos AU - Tsigris, Chris and AU - Giannopoulos, Athanasios AU - Bastounis, Elias JO - European Journal of Radiology PY - 2008 VL - 65 TODO - 3 SP - 427-433 PB - Elsevier Ireland Ltd SN - 0720-048X TODO - 10.1016/j.ejrad.2007.05.004 TODO - carotid artery ultrasound; B-mode; speckle; reverberation artifacts; image quality improvement TODO - Background and purpose: Speckle Reduction Imaging is a new algorithm that improves the image quality of B-mode scanning by reducing the reverberation artifacts. In the present study the value of this method for the characterization of atherosclerotic plaques in the internal carotid artery was investigated. Methods: Two hundred and twenty two patients (161 men, 61 women; mean age 73 years) referred for carotid ultrasound evaluation were included in the study. Patients with plaques of the internal carotid artery as identified by conventional B-mode scanning were investigated also with the addition of Speckle Reduction Imaging (SRI) with the use of a 4-11-MHz wide band linear transducer. Plaque morphology was rated according to a standardized protocol by two independent observers. Results: For the determination of plaque echogenicity, the reproducibility of SRI (k = 0.83) was higher than that of conventional B-mode ultrasound (k = 0.68). The interobserver agreement for plaque surface characterization was also higher for SRI (k = 0.8) than for conventional B-mode (k = 0.61). At the evaluation of the image quality through a semiquantitative analysis, SRI was rated superior in the plaque texture resolution, plaque borders determination, vessel wall demarcation and fibrous cap depiction. In addition, the level of “speckle” was reduced with the use of SRI. Conclusions: SRI is a technique that shows good general agreement with high-resolution B-mode and can be used for the characterization of atherosclerotic plaques in the carotid artery. Furthermore, because this advanced technique allows reduction of ultrasound artifacts, it improves the image quality allowing more precise visualization of plaque morphological details. (C) 2007 Elsevier Ireland Ltd. All rights reserved. ER -