TY - JOUR TI - Meal-induced thermogenesis and macronutrient oxidation in lean and obese women after consumption of carbohydrate-rich and fat-rich meals AU - Tentolouris, Nicholas AU - Alexiadou, Kleopatra AU - Kokkinos, Alexander AU - and Koukou, Eustathia AU - Perrea, Despoina AU - Kyriaki, Despoina and AU - Katsilambros, Nicholas JO - Frontiers in Nutrition PY - 2011 VL - 27 TODO - 3 SP - 310-315 PB - EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC SN - null TODO - 10.1016/j.nut.2010.02.007 TODO - Obesity; Diet-induced thermogenesis; Protein oxidation; Fat oxidation; Glucose oxidation TODO - Objective: To examine differences in meal-induced thermogenesis and macronutrient oxidation between lean and obese women after consumption of two different isocaloric meals, one rich in carbohydrate (CHO) and one rich in fat. Methods: A total of 19 lean and 22 obese women were studied on two occasions, 1 wk apart. In one visit they consumed a CHO-rich meal and in the other visit a fat-rich meal. The two meals were isocaloric and were given in random order. Resting energy expenditure and macronutrient oxidation rates were measured and calculated in the fasting state and every hour for 3 h after meal consumption. Results: Meal-induced thermogenesis was not different between lean and obese subjects after the CHO-rich (P = 0.89) or fat-rich (P = 0.32) meal, but it was significantly higher after the CHO-rich compared with the fat-rich meal in the lean and the obese individuals (P < 0.05). Protein oxidation rate increased slightly but significantly after the test meals in both groups (P < 0.01). Fat oxidation rate decreased after consumption of the CHO-rich meal (P < 0.001), whereas it increased after consumption of the fat-rich meal in both groups (P < 0.01). CHO oxidation rate increased in both groups after consumption of the CHO-rich meal (P < 0.001). Oxidation rates of protein, fat, and CHO during the experiment were not significantly different between lean and obese participants. Conclusion: Meal-induced thermogenesis and macronutrient oxidation rates were not significantly different between lean and obese women after consumption of a CHO-rich or a fat-rich meal. (C) 2011 Elsevier Inc. All rights reserved. ER -