TY - JOUR TI - Surgery-related Complications of Robot-assisted Radical Cystectomy With Intracorporeal Urinary Diversion AU - Schumacher, Martin C. AU - Jonsson, Martin N. AU - Hosseini, Abolfazl and AU - Nyberg, Tommy AU - Poulakis, Vassilis AU - Pardalidis, Nikolaos P. and AU - John, Hubert AU - Wiklund, Peter N. JO - European urology oncology PY - 2011 VL - 77 TODO - 4 SP - 871-876 PB - EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC SN - null TODO - 10.1016/j.urology.2010.11.035 TODO - null TODO - OBJECTIVES To assess the surgery-related complications at robot-assisted radical cystectomy with total intracorporeal urinary diversion during our learning curve in treating 45 patients with bladder cancer. METHODS A total of 45 patients were pooled in 3 consecutive groups of 15 cases each to evaluate the complications according to the Clavien classification. As a surrogate for our learning curve, the following parameters were assessed: operative time, blood loss, urinary diversion type, lymph node yield, surgical margin status, and length of hospital stay. RESULTS Early surgery-related complications were noted in 40% of the patients and late complications in 30%. The early Clavien grade III complications remained significant (27%) and did not decline with time. Overall, fewer complications were observed between the groups over time, with a significant decrease in late versus early complications (P = .005 and P = .058). The mean operative times declined from the first group to the second and third groups (P = .005) and the hospital stays shortened (P = .006). No significant difference was observed between groups regarding the lymph node yield at cystectomy (P = .108), with a mean of 22.5 nodes (range 10-52) removed. More patients received an orthotopic bladder substitute (Studer) in each of the latter 2 groups than in the first. CONCLUSIONS Although robot-assisted radical cystectomy with total intracorporeal urinary diversion is a complex procedure, we observed decreased surgery-related complications and improved outcomes over time in the present series. Our results need to be confirmed by others before robot-assisted radical cystectomy with totally intracorporeal urinary diversion can be accepted as a treatment option for patients with bladder cancer. UROLOGY 77: 871-877, 2011. (c) 2011 Elsevier Inc. ER -