TY - JOUR TI - Three Dimensional Power Doppler evaluation of human endometrium after administration of oxytocine receptor antagonist (OTRa) in an IVF program AU - Kalmantis, Konstantinos AU - Loutradis, Dimitrios AU - Lymperopoulos, AU - Elias AU - Beretsos, Panagiotis AU - Bletsa, Ritsa AU - Antsaklis, Aris JO - Archives of Gynecology and Obstetrics PY - 2012 VL - 285 TODO - 1 SP - 265-270 PB - Springer Berlin Heidelberg SN - 0932-0067, 1432-0711 TODO - 10.1007/s00404-011-2019-2 TODO - 3D Power Doppler; IVF; Endometrial receptivity; Oxytocine receptor antagonist TODO - Purpose To compare endometrial and subendometrial morphological changes and vascularity as measured by 3D Power Doppler sonography, based on a specific scoring system between women subjected or not to oxytocine receptor antagonist (OTRa) during IVF cycles. Methods Twenty-six women were divided into groups according to OTRa (Atosiban tractocide) administration. The first group (control n = 13 women) was examined with 3D Power Doppler 3 days after embryo transfer. The second group (n = 13 women) was administered 7.5 mg intravenous tractocide 2 days after embryo transfer and a 3D Power Doppler was performed after a day. Results The control group presented the following ultrasonographic characteristics: (a) echogenic endometrium in all cases, (b) endometrial thickness >7 mm in all cases (84.6%), (c) endometrial volume >2.31 cm(3) in 5 cases (38.5%), (d) abnormal sub-endometrial halo in 3 cases (23.1%), (e) endometrial blood flow in 6 cases (46.2%) and (f) complex vessel’s architecture in 2 cases (15.4%). In women who underwent OTRa administration were observed: (a) echogenic endometrium in 1 case (7.7%), triple line endometrium in 12 cases (92.3%), (b) endometrial thickness >7 mm in all cases, (c) endometrial volume >2.31 cm(3) in 11 cases (84.6%), (d) abnormal sub-endometrial halo in 3 cases (23.1%), (e) endometrial blood flow in 11 cases (84.6%) and (f) complex vessel’s architecture in 6 cases (46.2%). Conclusions Women who have taken OTRa presented an endometrium with characteristics more predictive of implantation. ER -