TY - JOUR TI - Incidence of non-infectious `acute mastoiditis' in children AU - Kontorinis, G. AU - Psarommatis, I. AU - Karabinos, C. AU - Iliodromiti, Z. AU - and Tsakanikos, M. JO - JOURNAL OF LARYNGOLOGY AND OTOLOGY PY - 2012 VL - 126 TODO - 3 SP - 244-248 PB - Cambridge University Press SN - 0022-2151 TODO - 10.1017/S0022215111002921 TODO - Chloroma; Facial Nerve Paralysis; Histopathology; Langerhans’ Cell Histiocytosis; Leukaemia; Mastoiditis TODO - Objective: The temporal bone may be the first involved site in cases of systemic disease, and may even present with acute, mastoiditis-like symptomatology. This study aimed to evaluate the incidence of such non-infectious ‘acute mastoiditis’ in children. Materials and methods: Retrospective chart review of 73 children admitted to a tertiary referral centre for acute mastoiditis. Results: In 71 cases (97.3 per cent), an infectious basis was identified. In the majority of cases (33 of 73; 45 per cent), the responsible bacteria was Streptococcus pneumoniae. However, histopathological studies revealed a non-infectious underlying disease (myelocytic leukaemia or Langerhans’ cell histiocytosis) in two atypical cases (2.7 per cent). Conclusion: ‘Acute mastoiditis’ of non-infectious aetiology is a rare but real threat for children, and a challenging diagnosis for otologists. A non-infectious basis should be suspected in every atypical, persistent or recurrent case of acute mastoiditis. ER -