TY - JOUR
TI - Myocardial Structure and Matrix Metalloproteinases
AU - Aggeli, C.
AU - Pietri, P.
AU - Felekos, I.
AU - Rautopoulos, L. and
AU - Toutouzas, K.
AU - Tsiamis, E.
AU - Stefanadis, C.
JO - Current Topics in Medicinal Chemistry
PY - 2012
VL - 12
TODO - 10
SP - 1113-1131
PB - BENTHAM SCIENCE PUBL LTD
SN - 1568-0266
TODO - 10.2174/1568026611208011113
TODO - Metaloproteinases; myocardial structure
TODO - Metalloproteinases (MMPs) are enzymes which enhance proteolysis of
extracellular matrix proteins. The pathophysiologic and prognostic role
of MMPs has been demonstrated in numerous studies. The present review
covers a wide a range of topics with regards to MMPs structural and
functional properties, as well as their role in myocardial remodeling in
several cardiovascular diseases. Moreover, the clinical and therapeutic
implications from their assessment are highlighted.
ER -