TY - JOUR
TI - Duloxetine Versus Citalopram and Sertraline in the Treatment of
Poststroke Depression, Anxiety, and Fatigue
AU - Karaiskos, Dimitrios
AU - Tzavellas, Elias
AU - Spengos, Konstantinos and
AU - Vassilopoulou, Sofia
AU - Paparrigopoulos, Thomas
JO - Journal of Neuropsychiatry and Clinical Neurosciences
PY - 2012
VL - 24
TODO - 3
SP - 349-353
PB - AMER PSYCHIATRIC PUBLISHING, INC
SN - 0895-0172, 1545-7222
TODO - 10.1176/appi.neuropsych.11110325
TODO - null
TODO - The authors sought to determine the relative efficacy and tolerability
of duloxetine versus citalopram and sertraline in the treatment of
poststroke depression (PSD), anxiety, and fatigue. A group of 60
patients with PSD were assigned to receive duloxetine, citalopram, or
sertraline and were assessed over a 3-month period for depression,
anxiety, and fatigue. Improvement of depression and anxiety, but not
fatigue, was observed in all study groups. Duloxetine was well tolerated
and significantly more effective than citalopram and sertraline for the
treatment of anxiety symptoms in PSD patients. None of the
antidepressants used was effective for reducing symptoms of fatigue.
(The Journal of Neuropsychiatry and Clinical Neurosciences 2012;
24:349-353)
ER -