TY - JOUR
TI - Is concordance with World Cancer Research Fund/American Institute for
Cancer Research guidelines for cancer prevention related to subsequent
risk of cancer? Results from the EPIC study
AU - Romaguera, Dora
AU - Vergnaud, Anne-Claire
AU - Peeters, Petra H.
AU - van
AU - Gils, Carla H.
AU - Chan, Doris S. M.
AU - Ferrari, Pietro
AU - Romieu,
AU - Isabelle
AU - Jenab, Mazda
AU - Slimani, Nadia
AU - Clavel-Chapelon,
AU - Francoise
AU - Fagherazzi, Guy
AU - Perquier, Florence
AU - Kaaks, Rudolf
AU - and Teucher, Birgit
AU - Boeing, Heiner
AU - von Ruesten, Anne and
AU - Tjonneland, Anne
AU - Olsen, Anja
AU - Dahm, Christina C.
AU - Overvad, Kim
AU - and Ramon Quiros, Jose
AU - Gonzalez, Carlos A.
AU - Jose Sanchez, Maria
AU - and Navarro, Carmen
AU - Barricarte, Aurelio
AU - Dorronsoro, Miren and
AU - Khaw, Kay-Tee
AU - Wareham, Nicholas J.
AU - Crowe, Francesca L.
AU - Key,
AU - Timothy J.
AU - Trichopoulou, Antonia
AU - Lagiou, Pagona
AU - Bamia,
AU - Christina
AU - Masala, Giovanna
AU - Vineis, Paolo
AU - Tumino, Rosario and
AU - Sieri, Sabina
AU - Panico, Salvatore
AU - May, Anne M. and
AU - Bueno-de-Mesquita, H. Bas
AU - Buechner, Frederike L.
AU - Wirfaelt,
AU - Elisabet
AU - Manjer, Jonas
AU - Johansson, Ingegerd
AU - Hallmans, Goeran
AU - and Skeie, Guri
AU - Benjaminsen Borch, Kristin
AU - Parr, Christine L.
AU - and Riboli, Elio
AU - Norat, Teresa
JO - AMERICAN JOURNAL OF CLINICAL NUTRITION
PY - 2012
VL - 96
TODO - 1
SP - 150-163
PB - Oxford University Press
SN - 0002-9165
TODO - 10.3945/ajcn.111.031674
TODO - null
TODO - Background: In 2007 the World Cancer Research Fund (WCRF) and the
American Institute of Cancer Research (AICR) issued 8 recommendations
(plus 2 special recommendations) on diet, physical activity, and weight
management for cancer prevention on the basis of the most comprehensive
collection of available evidence.
Objective: We aimed to investigate whether concordance with the
WCRF/AICR recommendations was related to cancer risk in the European
Prospective Investigation into Cancer and Nutrition (EPIC) study.
Design: The present study included 386,355 EPIC participants from 9
European countries. At recruitment, dietary, anthropometric, and
lifestyle information was collected. A score was constructed based on
the WCRF/AICR recommendations on weight management, physical activity,
foods and drinks that promote weight gain, plant foods, animal foods,
alcoholic drinks, and breastfeeding for women; the score range was 0-6
for men and 0-7 for women. Higher scores indicated greater concordance
with WCRF/AICR recommendations. The association between the score and
cancer risk was estimated by using multivariable Cox regression models.
Results: Concordance with the score was significantly associated with
decreased risk of cancer. A 1-point increment in the score was
associated with a risk reduction of 5% (95% Cl: 3%, 7%) for total
cancer, 12% (95% CI: 9%, 16%) for colorectal cancer, and 16% (95%
CI: 9%, 22%) for stomach cancer. Significant associations were also
observed for cancers of the breast, endometrium, lung, kidney, upper
aerodigestive tract, liver, and esophagus but not for prostate, ovarian,
pancreatic, and bladder cancers.
Conclusion: Adherence to the WCRF/AICR recommendations for cancer
prevention may lower the risk of developing most types of cancer. Am J
Clin Nutr 2012;96:150-63.
ER -