TY - JOUR
TI - MicroRNAs in Cardiovascular Therapeutics
AU - Siasos, Gerasimos
AU - Tousoulis, Dimitris
AU - Tourikis, Panagiotis and
AU - Mazaris, Savas
AU - Zakynthinos, Giorgos
AU - Oikonomou, Evangelos and
AU - Kokkou, Eleni
AU - Kollia, Christina
AU - Stefanadis, Christodoulos
JO - Current Topics in Medicinal Chemistry
PY - 2013
VL - 13
TODO - 13
SP - 1605-1618
PB - BENTHAM SCIENCE PUBL LTD
SN - 1568-0266
TODO - 10.2174/15680266113139990109
TODO - microRNAs; cardiovascular disease; therapy; atherosclerosis
TODO - Recent research reveals the crucial role microRNAs (miRNAs) in the
pathogenesis and progression of many pathological conditions, including
cardiovascular diseases. It is widely documented that miRNAs represent
critical regulators of cardiovascular function and participate in almost
all aspects of cardiovascular biology. In particular, they are involved
in several pathophysiological pathways of various manifestations of
cardiovascular disease, such as coronary artery disease, heart failure,
stroke, diabetes mellitus, arterial hypertension and cardiac
arrhythmias. In the present article we review the available literature
regarding to the role of miRNAs in certain cardiovascular conditions.
Moreover, we discuss the therapeutic potential of miRNAs for treating
cardiovascular diseases and we attempt to highlight future directions.
ER -