TY - JOUR TI - MICROBIOLOGY OF ACUTE MASTOIDITIS AND COMPLICATED OR REFRACTORY ACUTE OTITIS MEDIA AMONG HOSPITALIZED CHILDREN IN THE POSTVACCINATION ERA AU - Giannakopoulos, Polyvios AU - Chrysovergis, Aristeidis AU - Xirogianni, AU - Athanasia AU - Nikolopoulos, Thomas P. AU - Radiotis, Alexandros and AU - Lebessi, Evangelia AU - Tsakanikos, Michail AU - Tzanakaki, Georgina and AU - Tsolia, Maria N. JO - The Pediatric Infectious Disease Journal PY - 2014 VL - 33 TODO - 1 SP - 111-113 PB - Lippincott, Williams & Wilkins SN - 0891-3668, 1532-0987 TODO - 10.1097/INF.0b013e3182a6adb7 TODO - acute mastoiditis; refractory acute otitis media; complicated acute otitis media; Streptococcus pneumoniae serotype 19A; conjugate pneumococcal vaccine-heptavalent pneumococcal conjugate vaccine TODO - In the post-heptavalent pneumococcal conjugate vaccine era, Streptococcus pneumoniae remains the leading cause of acute mastoiditis and other complicated or refractory acute otitis media among hospitalized children in our settings. Serotype 19A is predominant, invasive and multidrug resistant causing more than half of all mastoiditis cases, two-thirds of cases with subperiosteal abscess and all those requiring mastoidectomy. Continuous surveillance is required. ER -