TY - JOUR TI - Concurrent pleural infiltration by chronic lymphocytic leukemia and adenocarcinoma of unknown primary site diagnosed by effusion cytology AU - Vrettos, Ioannis AU - Kamposioras, Konstantinos AU - Peridis, Stamatios AU - and Aninos, Dionisios AU - Kazika, Stella AU - Spathis, Aris and AU - Karakitsos, Petros AU - Papadopoulos, Angelos JO - Diagnostic Cytopathology PY - 2014 VL - 42 TODO - 2 SP - 151-155 PB - Wiley-Blackwell SN - 8755-1039, 1097-0339 TODO - 10.1002/dc.22889 TODO - B-CLL; unknown primary; synchronous; pleural effusion; adenocarcinoma TODO - Synchronous malignancies in a pleural effusion are rare. A case of concurrent pleural infiltration by adenocarcinoma of unknown primary site and chronic lymphocytic leukemia (CLL) is presented in this case study, which was diagnosed by effusion cytology. Pleural effusion is not an uncommon complication in patients with B-CLL. Even in a pleural effusion rich in monoclonal lymphocytes, the presence of a second cancer must be excluded because this can be the main cause of mortality. The role of cytology in such cases is of paramount importance. Diagn. Cytopathol. 2014;42:151-155. (c) 2012 Wiley Periodicals, Inc. ER -