TY - JOUR TI - Soy- and Rice-Based Formula and Infant Allergic to Cow's Milk AU - Tzifi, Flora AU - Grammeniatis, Vasilis AU - Papadopoulos, Marios JO - Endocrine, Metabolic & Immune Disorders - Drug Targets PY - 2014 VL - 14 TODO - 1 SP - 38-46 PB - BENTHAM SCIENCE PUBL LTD SN - 1871-5303 TODO - 10.2174/1871530314666140121144604 TODO - Children; cow’s milk allergy; rice allergenicity; rice formulas; soy allergenicity; soy formulas TODO - Soy milk formula has limited medical indications for infants feeding, although in several parts of the world it has been used as a source of nutrition in a large number of children. It used to be the main alternative feeding for infants allergic to cow’s milk who did not breastfeed before the introduction of extensively hydrolyzed formulas. Although there is a debate, the fact that some children are allergic to soy or some children with cow’s milk allergy can present with concomitant soy allergy, restricted the use of soy formulas for treatment of infants allergic to cow’s milk. Other grain-based formulas like the rice-based ones are promising in infants with cow’s milk allergy. Grain-based formulas could be an alternative and cheaper way of nutrition for infants allergic to cow’s milk than extensively hydrolyzed formulas. Further large scale longitudinal clinical studies are required to clarify the safety of soy and other grain-based formulas for treatment of cow’s milk allergy. ER -