TY - JOUR
TI - Dietary Fat Intake and Development of Specific Breast Cancer Subtypes
AU - Sieri, Sabina
AU - Chiodini, Paolo
AU - Agnoli, Claudia
AU - Pala, Valeria
AU - and Berrino, Franco
AU - Trichopoulou, Antonia
AU - Benetou, Vassiliki and
AU - Vasilopoulou, Effie
AU - Sanchez, Maria-Jose
AU - Chirlaque, Maria-Dolores
AU - and Amiano, Pilar
AU - Ramon Quiros, J.
AU - Ardanaz, Eva
AU - Buckland,
AU - Genevieve
AU - Masala, Giovanna
AU - Panico, Salvatore
AU - Grioni, Sara
AU - and Sacerdote, Carlotta
AU - Tumino, Rosario
AU - Boutron-Ruault,
AU - Marie-Christine
AU - Clavel-Chapelon, Francoise
AU - Fagherazzi, Guy and
AU - Peeters, Petra H. M.
AU - van Gils, Carla H.
AU - Bueno-de-Mesquita, H.
AU - Bas
AU - van Kranen, Henk J.
AU - Key, Timothy J.
AU - Travis, Ruth C. and
AU - Khaw, Kay Tee
AU - Wareham, Nicholas J.
AU - Kaaks, Rudolf
AU - Lukanova,
AU - Annekatrin
AU - Boeing, Heiner
AU - Schuetze, Madlen
AU - Sonestedt, Emily
AU - and Wirfaelt, Elisabeth
AU - Sund, Malin
AU - Andersson, Anne
AU - Chajes,
AU - Veronique
AU - Rinaldi, Sabina
AU - Romieu, Isabelle
AU - Weiderpass,
AU - Elisabete
AU - Skeie, Guri
AU - Dagrun, Engeset
AU - Tjonneland, Anne and
AU - Halkjaer, Jytte
AU - Overvard, Kim
AU - Merritt, Melissa A.
AU - Cox, David
AU - and Riboli, Elio
AU - Krogh, Vittorio
JO - JNCI Journal of the National Cancer Institute
PY - 2014
VL - 106
TODO - 5
SP - null
PB - OXFORD UNIV PRESS INC
SN - 0027-8874, 1460-2105
TODO - 10.1093/jnci/dju068
TODO - null
TODO - We prospectively evaluated fat intake as predictor of developing breast
cancer (BC) subtypes defined by estrogen receptor (ER), progesterone
receptor (PR), and human epidermal growth factor 2 receptor (HER2), in a
large (n = 337 327) heterogeneous cohort of women, with 10 062 BC case
patients after 11.5 years, estimating BC hazard ratios (HRs) by Cox
proportional hazard modeling. High total and saturated fat were
associated with greater risk of ER+PR+ disease (HR = 1.20, 95%
confidence interval [CI] = 1.00 to 1.45; HR = 1.28, 95% CI = 1.09 to
1.52; highest vs lowest quintiles) but not ER-PR- disease. High
saturated fat was statistically significantly associated with greater
risk of HER2(-) disease. High saturated fat intake particularly
increases risk of receptor-positive disease, suggesting saturated fat
involvement in the etiology of this BC subtype.
ER -