TY - JOUR
TI - The effect of consumption of low-glycemic-index and low-glycemic-load
desserts on anthropometric parameters and inflammatory markers in
patients with type 2 diabetes mellitus
AU - Argiana, Vasiliki
AU - Kanellos, Panagiotis T.
AU - Makrilakis,
AU - Konstantinos
AU - Eleftheriadou, Ioanna
AU - Tsitsinakis, Georgios and
AU - Kokkinos, Alexander
AU - Perrea, Despina
AU - Tentolouris, Nikolaos
JO - European Journal of Nutrition
PY - 2015
VL - 54
TODO - 7
SP - 1173-1180
PB - Springer Berlin Heidelberg
SN - 1436-6207, 1436-6215
TODO - 10.1007/s00394-014-0795-8
TODO - Glycemic index; Glycemic load; Lipids; Low-grade inflammation; Type 2
diabetes mellitus
TODO - The aim of the present study was to examine the effects of consumption
of desserts with low glycemic index (GI) and low glycemic load (GL), as
part of a balanced hypo-caloric diet, on anthropometric and biochemical
parameters in patients with type 2 diabetes mellitus (T2DM).
A total of 61 subjects with T2DM were randomly assigned to the
intervention (n = 30) or to the control group (n = 31). Both groups
followed the same hypo-caloric (-500 kcal) diet for 12 weeks.
Consumption of four portions of low-GI/low-GL desserts/week was included
in the diet in the intervention group while one portion of a favorite
usual sweet/week was allowed to be consumed in the control group.
Thirty subjects in the control and 28 subjects in the intervention group
completed the trial. Body weight, body mass index, and waist
circumference were reduced significantly in both groups. Arterial blood
pressure, fasting blood glucose, glycosylated hemoglobin, insulin, and
gamma-GT were reduced significantly only in the intervention group;
however, there were no significant differences between the two groups at
endpoint. C-reactive protein was reduced in the intervention, and HDL
cholesterol was also reduced in the control group; the reductions were
significantly different at the end of the trial. No significant changes
were observed in the other plasma lipids, uric acid, leptin,
adiponectin, and interleukin-6 in either study group.
Consumption of desserts with low GI/GL in a balanced hypo-caloric diet
has a positive impact on anthropometric and metabolic parameters of
patients with T2DM.
ER -