TY - CONF TI - Complex Dynamics in Tumor Gene Regulatory Networks: Oncogenesis Dynamics Driven by “Genes Gone Crazy” AU - Lambrou, G. I. AU - Braoudaki, M. AU - Katrakazas, P. AU - Kouris, I. and AU - Iliopoulou, D. AU - Koutsouri, Tz. AU - Petropoulou, O. AU - Koutsouris, D. AU - -D. PY - 2016 SP - 501-505 PB - Springer-Verlag T2 - XIV MEDITERRANEAN CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 2016 TODO - 10.1007/978-3-319-32703-7_97 TODO - Microarray; pathway; gene expression; complex dynamics; sink; oscillations TODO - Human neoplasms are considered to be diseases whose pathogenesis is attributed to genomic aberrations. Yet, it has been previously reported that genomic stability is probably not the sole “player” in tumor ontogenesis. Several genes have been identified that are considerd to be the “oncogenic drivers”. In that sense the present work manifests a hypothesis that tumor ontogenesis could be driven by genes or network of genes that get out of control or else “genes gone crazy”. ER -