TY - JOUR
TI - Intracranial pressure, its components and cerebrospinal fluid
pressure-volume compensation
AU - Kasprowicz, M.
AU - Lalou, D. A.
AU - Czosnyka, M.
AU - Garnett, M. and
AU - Czosnyka, Z.
JO - Acta Neurologica Scandinavica
PY - 2016
VL - 134
TODO - 3
SP - 168-180
PB - Wiley
SN - 0001-6314, 1600-0404
TODO - 10.1111/ane.12541
TODO - cerebrospinal fluid dynamics; constant-rate infusion test; intracranial
pressure; overnight monitoring
TODO - Clinical measurement of intracranial pressure (ICP) is often performed
to aid diagnosis of hydrocephalus. This review discusses analysis of ICP
and its components' for the investigation of cerebrospinal fluid (CSF)
dynamics. The role of pulse, slow and respiratory waveforms of ICP in
diagnosis, prognostication and management of hydrocephalus is presented.
Two methods related to ICP measurement are listed: an overnight
monitoring of ICP and a constant-rate infusion study. Due to the dynamic
nature of ICP, a snapshot' manometric measurement of ICP is of limited
use as it might lead to unreliable results. Therefore, monitoring of ICP
over longer time combined with analysis of its waveforms provides more
detailed information on the state of pressure-volume compensation. The
infusion study implements ICP signal processing and CSF circulation
model analysis in order to assess the cerebrospinal dynamics variables,
such as CSF outflow resistance, compliance of CSF space, pressure
amplitude, reference pressure, and CSF formation. These parameters act
as an aid tool in diagnosis and prognostication of hydrocephalus and can
be helpful in the assessment of a shunt malfunction.
ER -