TY - JOUR
TI - Main nutrient patterns are associated with prospective weight change in
adults from 10 European countries
AU - Freisling, Heinz
AU - Pisa, Pedro T.
AU - Ferrari, Pietro
AU - Byrnes,
AU - Graham
AU - Moskal, Aurelie
AU - Dahm, Christina C.
AU - Vergnaud,
AU - Anne-Claire
AU - Boutron-Ruault, Marie-Christine
AU - Fagherazzi, Guy and
AU - Cadeau, Claire
AU - Kuehn, Tilman
AU - Neamat-Allah, Jasmine
AU - Buijsse,
AU - Brian
AU - Boeing, Heiner
AU - Halkjaer, Jytte
AU - Tjonneland, Anne and
AU - Hansen, Camilla P.
AU - Ramon Quiros, J.
AU - Travier, Noemie and
AU - Molina-Montes, Esther
AU - Amiano, Pilar
AU - Huerta, Jose M. and
AU - Barricarte, Aurelio
AU - Khaw, Kay-Tee
AU - Wareham, Nicholas
AU - Key, Tim
AU - J.
AU - Romaguera, Dora
AU - Lu, Yunxia
AU - Lassale, Camille M.
AU - Naska,
AU - Androniki
AU - Orfanos, Philippos
AU - Trichopoulou, Antonia
AU - Masala,
AU - Giovanna
AU - Pala, Valeria
AU - Berrino, Franco
AU - Tumino, Rosario and
AU - Ricceri, Fulvio
AU - de Magistris, Maria Santucci
AU - Bueno-de-Mesquita,
AU - H. Bas
AU - Ocke, Marga C.
AU - Sonestedt, Emily
AU - Ericson, Ulrika and
AU - Johansson, Mattias
AU - Skeie, Guri
AU - Weiderpass, Elisabete and
AU - Braaten, Tonje
AU - Peeters, Petra H. M.
AU - Slimani, Nadia
JO - European Journal of Nutrition
PY - 2016
VL - 55
TODO - 6
SP - 2093-2104
PB - Springer Berlin Heidelberg
SN - 1436-6207, 1436-6215
TODO - 10.1007/s00394-015-1023-x
TODO - Dietary patterns; Nutrients; Weight gain; Obesity; Energy balance;
Public health
TODO - Various food patterns have been associated with weight change in adults,
but it is unknown which combinations of nutrients may account for such
observations. We investigated associations between main nutrient
patterns and prospective weight change in adults.
This study includes 235,880 participants, 25-70 years old, recruited
between 1992 and 2000 in 10 European countries. Intakes of 23 nutrients
were estimated from country-specific validated dietary questionnaires
using the harmonized EPIC Nutrient DataBase. Four nutrient patterns,
explaining 67 % of the total variance of nutrient intakes, were
previously identified from principal component analysis. Body weight was
measured at recruitment and self-reported 5 years later. The
relationship between nutrient patterns and annual weight change was
examined separately for men and women using linear mixed models with
random effect according to center controlling for confounders.
Mean weight gain was 460 g/year (SD 950) and 420 g/year (SD 940) for men
and women, respectively. The annual differences in weight gain per one
SD increase in the pattern scores were as follows: principal component
(PC) 1, characterized by nutrients from plant food sources, was
inversely associated with weight gain in men (-22 g/year; 95 % CI -33
to -10) and women (-18 g/year; 95 % CI -26 to -11). In contrast, PC4,
characterized by protein, vitamin B2, phosphorus, and calcium, was
associated with a weight gain of +41 g/year (95 % CI +2 to +80) and +88
g/year (95 % CI +36 to +140) in men and women, respectively.
Associations with PC2, a pattern driven by many micro-nutrients, and
with PC3, a pattern driven by vitamin D, were less consistent and/or
non-significant.
We identified two main nutrient patterns that are associated with
moderate but significant long-term differences in weight gain in adults.
ER -