TY - JOUR TI - A novel Hemi-Body Irradiation technique using electron beams (HBIe(-)) AU - Delinikolas, Panagiotis AU - Patatoukas, Georgios AU - Kouloulias, AU - Vasilios AU - Dilvoi, Maria AU - Plousi, Agapi AU - Efstathopoulos, AU - Efstathios AU - Platoni, Kalliopi JO - PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS PY - 2018 VL - 46 TODO - null SP - 16-24 PB - Elsevier Sci Ltd, Exeter, United Kingdom SN - null TODO - 10.1016/j.ejmp.2017.12.022 TODO - Half-body skin irradiation; Stanford technique; Kaposi's sarcoma; T-cell lymphoma TODO - Purpose: Certain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe(-)) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques. Materials and methods: The HBIe(-) technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is positioned in ‘Stanford’ technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at ‘Stanford’ angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields. Results: The resulting homogeneity of the surface dose in the treatment plane for an average patient was 5-6%, while surface dose homogeneity on the anthropomorphic phantom was 7% for both the upper and the lower HBIe(-) variants. The total PDD exhibits an almost linear decrease to a practical range of 2 g/cm(2). Conclusion: In conclusion, HBIe(-) was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin. ER -