TY - JOUR
TI - European evidence-based guidelines on pancreatic cystic neoplasms
AU - Del Chiaro, Marco
AU - Besselink, Marc G.
AU - Scholten, Lianne
AU - Bruno,
AU - Marco J.
AU - Cahen, Djuna L.
AU - Gress, Thomas M.
AU - van Hooft, Jeanin
AU - E.
AU - Lerch, Markus M.
AU - Mayerle, Julia
AU - Hackert, Thilo
AU - Satoi,
AU - Sohei
AU - Zerbi, Alessandro
AU - Cunningham, David
AU - De Angelis,
AU - Claudio
AU - Giovanni, Marc
AU - de-Madaria, Enrique
AU - Hegyi, Peter and
AU - Rosendahl, Jonas
AU - Friess, Helmut
AU - Manfredi, Riccardo
AU - Levy,
AU - Philippe
AU - Real, Francisco X.
AU - Sauvanet, Alain
AU - Abu Hilal,
AU - Mohammed
AU - Marchegiani, Giovanni
AU - Esposito, Irene
AU - Ghaneh, Paula
AU - and Engelbrecht, Marc R. W.
AU - Fockens, Paul
AU - van Huijgevoort,
AU - Nadine C. M.
AU - Wolfgang, Christopher
AU - Bassi, Claudio and
AU - Gubergrits, Natalya B.
AU - Verbeke, Caroline
AU - Kloppel, Gunter and
AU - Scarpa, Aldo
AU - Zamboni, Giuseppe
AU - Lennon, Anne Marie
AU - Sund,
AU - Malin
AU - Kartalis, Nikolaos
AU - Grenacher, Lars
AU - Falconi, Massimo
AU - and Arnelo, Urban
AU - Kopchak, Kostantin V.
AU - Oppong, Kofi
AU - McKay,
AU - Colin
AU - Hauge, Truls
AU - Conlon, Kevin
AU - Adham, Mustapha
AU - Ceyhan,
AU - Guralp O.
AU - Salvia, Roberto
AU - Dervenis, Christos
AU - Allen, Peter
AU - and Paye, Francois
AU - Bartsch, Detlef K.
AU - Lohr, Matthias and
AU - Mutignani, Massimiliano
AU - Laukkarinen, Johanna
AU - Schulick, Richard
AU - and Valente, Roberto
AU - Seufferlein, Thomas
AU - Capurso, Gabriele and
AU - Siriwardena, Ajith
AU - Neoptolemos, John P.
AU - Pukitis, Aldis and
AU - Segersvard, Ralf
AU - Aghdassi, A.
AU - Andrianello, S.
AU - Bossuyt, P.
AU - and Bulow, R.
AU - Cardenas-Jaen, K.
AU - Cortegoso, P.
AU - Fontana, M.
AU - and Haeberle, L.
AU - Heckler, M.
AU - Litvin, A.
AU - Mann, K. and
AU - Michalski, C.
AU - Michl, P.
AU - Nappo, G.
AU - Perri, G.
AU - Persson, S.
AU - and Scheufele, F.
AU - Sclafani, F.
AU - Schmidt, M.
AU - Venezia, L. and
AU - Volker, F.
AU - Vullierm, M-P
AU - Wusten, L.
AU - European Study Grp
AU - Cystic Tum
JO - Gut Pathogens
PY - 2018
VL - 67
TODO - 5
SP - 789-804
PB - BMJ Publishing Group
SN - 1757-4749
TODO - 10.1136/gutjnl-2018-316027
TODO - null
TODO - Evidence-based guidelines on the management of pancreatic cystic
neoplasms (PCN) are lacking. This guideline is a joint initiative of the
European Study Group on Cystic Tumours of the Pancreas, United European
Gastroenterology, European Pancreatic Club, European-African
Hepato-Pancreato-Biliary Association, European Digestive Surgery, and
the European Society of Gastrointestinal Endoscopy. It replaces the 2013
European consensus statement guidelines on PCN. European and
non-European experts performed systematic reviews and used GRADE
methodology to answer relevant clinical questions on nine topics
(biomarkers, radiology, endoscopy, intraductal papillary mucinous
neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm,
rare cysts, (neo)adjuvant treatment, and pathology). Recommendations
include conservative management, relative and absolute indications for
surgery. A conservative approach is recommended for asymptomatic MCN and
IPMN measuring < 40 mm without an enhancing nodule. Relative indications
for surgery in IPMN include a main pancreatic duct (MPD) diameter
between 5 and 9.9 mm or a cyst diameter >= 40 mm. Absolute indications
for surgery in IPMN, due to the high-risk of malignant transformation,
include jaundice, an enhancing mural nodule > 5 mm, and MPD diameter >
10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit
for surgery. The European evidence-based guidelines on PCN aim to
improve the diagnosis and management of PCN.
ER -