TY - JOUR TI - Systemic lupus erythematosus: state of the art on clinical practice guidelines AU - Tamirou, Farah AU - Arnaud, Laurent AU - Talarico, Rosaria AU - Scire, AU - Carlo Alberto AU - Alexander, Tobias AU - Amoura, Zahir AU - Avcin, Tadej AU - and Bortoluzzi, Alessandra AU - Cervera, Ricard AU - Conti, Fabrizio and AU - Cornet, Alain AU - Devilliers, Herve AU - Doria, Andrea AU - Frassi, Micol AU - and Fredi, Micaela AU - Govoni, Marcello AU - Houssiau, Frederic and AU - Llado, Ana AU - Macieira, Carla AU - Martin, Thierry AU - Massaro, Laura AU - and Moraes-Fontes, Maria Francisca AU - Pamfil, Cristina AU - Paolino, AU - Sabrina AU - Tani, Chiara AU - Tas, Sander W. AU - Tektonidou, Maria and AU - Tincani, Angela AU - Van Vollenhoven, Ronald F. AU - Bombardieri, Stefano AU - and Burmester, Gerd AU - Fonseca, Joao Eurico AU - Galetti, Ilaria and AU - Hachulla, Eric AU - Mueller-Ladner, Ulf AU - Schneider, Matthias and AU - Smith, Vanessa AU - Cutolo, Maurizio AU - Mosca, Marta and AU - Costedoat-Chalumeau, Nathalie JO - RMD Open: Rheumatic & Musculoskeletal Diseases PY - 2018 VL - 4 TODO - 1 SP - null PB - BMJ Publishing Group SN - 2056-5933 TODO - 10.1136/rmdopen-2018-000793 TODO - null TODO - Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing-remitting course. The aim of the present work was to identify current available clinical practice guidelines (CPGs) for SLE, to provide their review and to identify physicians' and patients' unmet needs. Twenty-three original guidelines published between 2004 and 2017 were identified. Many aspects of disease management are covered, including global disease management, lupus nephritis and neuropsychiatric involvement, management of pregnancies, vaccinations and comorbidities monitoring. Unmet needs relate with disease management of some clinical manifestations and adherence to treatment. Many patient's unmet needs have been identified starting with faster diagnosis, need for more therapeutic options, guidelines on lifestyle issues, attention to quality of life and adequate education. ER -