TY - JOUR TI - Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines AU - Schunemann, Holger J. AU - Lerda, Donata AU - Quinn, Cecily AU - Follmann, AU - Markus AU - Alonso-Coello, Pablo AU - Rossi, Paolo Giorgi AU - Lebeau, AU - Annette AU - Nystrom, Lennarth AU - Broeders, Mireille and AU - Ioannidou-Mouzaka, Lydia AU - Duffy, Stephen W. AU - Borisch, Bettina and AU - Fitzpatrick, Patricia AU - Hofvind, Solveig AU - Castells, Xavier and AU - Giordano, Livia AU - Canelo-Aybar, Carlos AU - Warman, Sue AU - Mansel, AU - Robert AU - Sardanelli, Francesco AU - Parmelli, Elena AU - Grawingholt, AU - Axel AU - Saz-Parkinson, Zuleika AU - ECIBC Contributor Grp JO - ANNALS OF INTERNAL MEDICINE PY - 2020 VL - 172 TODO - 1 SP - 46+ PB - AMER COLL PHYSICIANS SN - 0003-4819 TODO - 10.7326/M19-2125 TODO - null TODO - Description: The European Commission Initiative for Breast Cancer Screening and Diagnosis guidelines (European Breast Guidelines) are coordinated by the European Commission's Joint Research Centre. The target audience for the guidelines includes women, health professionals, and policymakers. Methods: An international guideline panel of 28 multidisciplinary members, including patients, developed questions and corresponding recommendations that were informed by systematic reviews of the evidence conducted between March 2016 and December 2018. GRADE (Grading of Recommendations Assessment, Development and Evaluation) Evidence to Decision frameworks were used to structure the process and minimize the influence of competing interests by enhancing transparency. Questions and recommendations, expressed as strong or conditional, focused on outcomes that matter to women and provided a rating of the certainty of evidence. Recommendations: This synopsis of the European Breast Guidelines provides recommendations regarding organized screening programs for women aged 40 to 75 years who are at average risk. The recommendations address digital mammography screening and the addition of hand-held ultrasonography, automated breast ultrasonography, or magnetic resonance imaging compared with mammography alone. The recommendations also discuss the frequency of screening and inform decision making for women at average risk who are recalled for suspicious lesions or who have high breast density. ER -