TY - JOUR TI - COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow AU - Bikdeli, Behnood AU - Madhavan, Mahesh V. AU - Jimenez, David AU - Chuich, AU - Taylor AU - Dreyfus, Isaac AU - Driggin, Elissa AU - Der Nigoghossian, AU - Caroline AU - Ageno, Walter AU - Madjid, Mohammad AU - Guo, Yutao AU - Tang, AU - Liang V. AU - Hu, Yu AU - Giri, Jay AU - Cushman, Mary AU - Quere, Isabelle AU - and Dimakakos, Evangelos P. AU - Gibson, C. Michael AU - Lippi, Giuseppe AU - and Favaloro, Emmanuel J. AU - Fareed, Jawed AU - Caprini, Joseph A. and AU - Tafur, Alfonso J. AU - Burton, John R. AU - Francese, Dominic P. AU - Wang, AU - Elizabeth Y. AU - Falanga, Anna AU - McLintock, Claire AU - Hunt, Beverley AU - J. AU - Spyropoulos, Alex C. AU - Barnes, Geoffrey D. AU - Eikelboom, John AU - W. AU - Weinberg, Ido AU - Schulman, Sam AU - Carrier, Marc AU - Piazza, AU - Gregory AU - Beckman, Joshua A. AU - Steg, Gabriel AU - Stone, Gregg W. and AU - Rosenkranz, Stephan AU - Goldhaber, Samuel Z. AU - Parikh, Sahil A. and AU - Monreal, Manuel AU - Krumholz, Harlan M. AU - Konstantinides, Stavros V. AU - and Weitz, Jeffrey I. AU - Lip, Gregory Y. H. AU - Global COVID-19 AU - Thrombosis Collabo AU - ISTH AU - NATF AU - ESVM AU - ESC Working Grp Pulm AU - Ci JO - Journal of the American College of Cardiology PY - 2020 VL - 75 TODO - 23 SP - 2950-2973 PB - EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC SN - 0735-1097, 1558-3597 TODO - 10.1016/j.jacc.2020.04.031 TODO - null TODO - Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), may predispose patients to thrombotic disease, both in the venous and arterial circulations, because of excessive inflammation, platelet activation, endothelial dysfunction, and stasis. In addition, many patients receiving antithrombotic therapy for thrombotic disease may develop COVID-19, which can have implications for choice, dosing, and laboratory monitoring of antithrombotic therapy. Moreover, during a time with much focus on COVID-19, it is critical to consider how to optimize the available technology to care for patients without COVID-19 who have thrombotic disease. Herein, the authors review the current understanding of the pathogenesis, epidemiology, management, and outcomes of patients with COVID-19 who develop venous or arterial thrombosis, of those with pre-existing thrombotic disease who develop COVID-19, or those who need prevention or care for their thrombotic disease during the COVID-19 pandemic. (J Am Coll Cardiol 2020;75:2950-73) (c) 2020 by the American College of Cardiology Foundation. ER -