TY - JOUR TI - Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis AU - Lyubenova, Anita AU - Neupane, Dipika AU - Levis, Brooke AU - Wu, Yin and AU - Sun, Ying AU - He, Chen AU - Krishnan, Ankur AU - Bhandari, Parash M. and AU - Negeri, Zelalem AU - Imran, Mahrukh AU - Rice, Danielle B. AU - Azar, AU - Marleine AU - Chiovitti, Matthew J. AU - Saadat, Nazanin AU - Riehm, Kira AU - E. AU - Boruff, Jill T. AU - Ioannidis, John P. A. AU - Cuijpers, Pim and AU - Gilbody, Simon AU - Kloda, Lorie A. AU - Patten, Scott B. AU - Shrier, Ian AU - and Ziegelstein, Roy C. AU - Comeau, Liane AU - Mitchell, Nicholas D. and AU - Tonelli, Marcello AU - Vigod, Simone N. AU - Aceti, Franca AU - Barnes, AU - Jacqueline AU - Bavle, Amar D. AU - Beck, Cheryl T. AU - Bindt, Carola and AU - Boyce, Philip M. AU - Bunevicius, Adomas AU - Chaudron, Linda H. and AU - Favez, Nicolas AU - Figueiredo, Barbara AU - Garcia-Esteve, Lluisa and AU - Giardinelli, Lisa AU - Helle, Nadine AU - Howard, Louise M. AU - Kohlhoff, AU - Jane AU - Kusminskas, Laima AU - Kozinszky, Zoltan AU - Lelli, Lorenzo and AU - Leonardou, Angeliki A. AU - Meuti, Valentina AU - Rados, Sandra N. and AU - Garcia, Purificacion N. AU - Pawlby, Susan J. AU - Quispel, Chantal and AU - Robertson-Blackmore, Emma AU - Rochat, Tamsen J. AU - Sharp, Deborah J. AU - and Siu, Bonnie W. M. AU - Stein, Alan AU - Stewart, Robert C. and AU - Tadinac, Meri AU - Tandon, S. Darius AU - Tendais, Iva AU - Toreki, AU - Annamaria AU - Torres-Gimenez, Anna AU - Tran, Thach D. AU - Trevillion, AU - Kylee AU - Turner, Katherine AU - Vega-Dienstmaier, Johann M. and AU - Benedetti, Andrea AU - Thombs, Brett D. JO - International Journal of Methods in Psychiatric Research PY - 2021 VL - 30 TODO - 1 SP - null PB - Wiley SN - 1049-8931, 1557-0657 TODO - 10.1002/mpr.1860 TODO - depression prevalence; Edinburgh Postnatal Depression Scale; structured clinical interview for DSM; individual participant data meta-analysis; major depression TODO - Objectives Estimates of depression prevalence in pregnancy and postpartum are based on the Edinburgh Postnatal Depression Scale (EPDS) more than on any other method. We aimed to determine if any EPDS cutoff can accurately and consistently estimate depression prevalence in individual studies. Methods We analyzed datasets that compared EPDS scores to Structured Clinical Interview for DSM (SCID) major depression status. Random-effects meta-analysis was used to compare prevalence with EPDS cutoffs versus the SCID. Results Seven thousand three hundred and fifteen participants (1017 SCID major depression) from 29 primary studies were included. For EPDS cutoffs used to estimate prevalence in recent studies (>= 9 to >= 14), pooled prevalence estimates ranged from 27.8% (95% CI: 22.0%-34.5%) for EPDS >= 9 to 9.0% (95% CI: 6.8%-11.9%) for EPDS >= 14; pooled SCID major depression prevalence was 9.0% (95% CI: 6.5%-12.3%). EPDS >= 14 provided pooled prevalence closest to SCID-based prevalence but differed from SCID prevalence in individual studies by a mean absolute difference of 5.1% (95% prediction interval: -13.7%, 12.3%). Conclusion EPDS >= 14 approximated SCID-based prevalence overall, but considerable heterogeneity in individual studies is a barrier to using it for prevalence estimation. ER -