TY - JOUR
TI - Cushing's syndrome in pregnancy: a review of reported cases
AU - Kyriakos, Georgios
AU - Farmaki, Paraskevi
AU - Voutyritsa, Errika and
AU - Patsouras, Alexandros
AU - Victoria Quiles-Sanchez, Lourdes
AU - Damaskos,
AU - Christos
AU - Stelianidi, Athanasia
AU - Pastor-Alcaraz, Adrian and
AU - Palomero-Entrenas, Patricia
AU - Diamantis, Evangelos
JO - Endokrynologia Polska
PY - 2021
VL - 72
TODO - 1
SP - 64-72
PB - Via Medica SP Zoo
SN - 0423-104X, 2299-8306
TODO - 10.5603/EP.a2021.0001
TODO - Cushing's syndrome; pregnancy; hypercortisolism; adrenocortical adenoma;
pituitary adenoma; review
TODO - Cushing's syndrome (CS) causes hypogonadotropic hypogonadism and
anovulatory infertility due to hypercortisolism, and it is very rare in
pregnancy. CS in pregnancy is associated with important maternal-foetal
morbidity and mortality, such as preeclampsia and premature delivery.
A systematic search was conducted in the MEDLINE library to retrieve
articles reporting cases of CS in pregnant women, during the period
between 2010 and 2020.
Thirty-five reported cases are presented focusing on the ability of
diagnosis, treatment therapies, and foetal outcomes. Diagnosis of CS
during pregnancy can be challenging and is often delayed, adrenal
adenoma being the predominant cause. Both medical treatment and surgery
aiming at restoring the cortisol balance reduce maternal and foetal
complications.
ER -