TY - JOUR
TI - Quality of Life among Patients with Retinal Vein Occlusion: A
Case-Control Study
AU - Chatzirallis, Alexandros
AU - Varaklioti, Agoritsa
AU - Sergentanis,
AU - Theodoros N.
AU - Theodossiadis, Panagiotis
AU - Chatziralli, Irini
JO - Seminars in Ophthalmology
PY - 2021
VL - 36
TODO - 8
SP - 658-664
PB - Taylor and Francis Inc.
SN - 0882-0538, 1744-5205
TODO - 10.1080/08820538.2021.1896750
TODO - Retinal vein occlusion; quality; VFQ-25; EQ-5D; risk factors
TODO - Purpose: The purpose of this study was to evaluate health-related
quality of life in patients with retinal vein occlusion (RVO) and
investigate the possible risk factors for poor quality of life in
patients with RVO.
Methods: Participants in the study were 67 patients with RVO, 42 male
and 25 female, mean-aged 73.1 +/- 10.9 years, and 70 sex- and
age-matched controls. Demographic data, lifestyle factors and medical
history were recorded. All patients underwent best-corrected visual
acuity measurement, dilated fundoscopy and optical coherence tomography.
All participants completed two questionnaires assessing quality of life
(EQ-5D, NEI VFQ-25). Risk factors for health-related quality of life in
RVO patients were investigated.
Results: Patients with RVO exhibited significantly lower composite score
for VFQ-25 compared to controls (74.1 +/- 3.8 vs. 91.7 +/- 3.9 for
patients and controls, respectively, p < .001). In addition, RVO
patients had significantly lower EQ-5D Index score compared to controls
(0.88 +/- 0.15 vs. 0.92 +/- 0.12 for patients and controls,
respectively, p = .043). Risk factors associated with quality of life in
patients with RVO were found the alcohol consumption, the presence of
thyroidopathy, coagulation disorders, visual acuity in the eye with RVO,
central retinal thickness, the type of edema, the presence of ischemia
and the condition of external limiting membrane. In multivariate
analysis, only alcohol consumption and visual acuity in the eye with RVO
were found to be independent risk factors, affecting quality of life in
RVO patients.
Conclusions: Patients with RVO presented lower quality of life in
comparison with controls. Potential risk factors should be taken into
account and their early detection may improve quality of life in such
patients and lead to targeted health policies.
ER -