TY - JOUR
TI - Consensus Guidelines for the Definition of Time-to-Event End Points in Image-guided Tumor Ablation: Results of the SIO and DATECAN Initiative.
AU - Puijk, Robbert S.
AU - Ahmed, Muneeb
AU - Adam, Andreas
AU - Arai, Yasuaki
AU - Arellano, Ronald
AU - de Baère, Thierry
AU - Bale, Reto
AU - Bellera, Carine
AU - Binkert, Christoph A.
AU - Brace, Christopher L.
AU - Breen, David J.
AU - Brountzos, Elias
AU - Callstrom, Matthew R.
AU - Carrafiello, Gianpaolo
AU - Chapiro, Julius
AU - de Cobelli, Francesco
AU - Coupé, Veerle M. H.
AU - Crocetti, Laura
AU - Denys, Alban
AU - Dupuy, Damian E.
AU - Erinjeri, Joseph P.
AU - Filippiadis, Dimitris
AU - Gangi, Afshin
AU - Gervais, Debra A.
AU - Gillams, Alice R.
AU - Greene, Tissy
AU - Guiu, Boris
AU - Helmberger, Thomas
AU - Iezzi, Roberto
AU - Kang, Tae Wook
AU - Kelekis, Alexis
AU - Kim, Hyun S.
AU - Kröncke, Thomas
AU - Kwan, Sharon
AU - Lee, Min Woo
AU - Lee, Fred T.
AU - Lee, Edward W. Jr
AU - Liang, Ping
AU - Lissenberg-Witte, Birgit I.
AU - Lu, David S.
AU - Madoff, David C.
AU - Mauri, Giovanni
AU - Meloni, Maria Franca
AU - Morgan, Robert
AU - Nadolski, Gregory
AU - Narayanan, Govindarajan
AU - Newton, Isabel
AU - Nikolic, Boris
AU - Orsi, Franco
AU - Pereira, Philippe L.
AU - Pua, Uei
AU - Rhim, Hyunchul
AU - Ricke, Jens
AU - Rilling, William
AU - Salem, Riad
AU - Scheffer, Hester J.
AU - Sofocleous, Constantinos T.
AU - Solbiati, Luigi A.
AU - Solomon, Stephen B.
AU - Soulen, Michael C.
AU - Sze, Daniel
AU - Uberoi, Raman
AU - Vogl, Thomas J.
AU - Wang, David S.
AU - Wood, Bradford J.
AU - Goldberg, S. Nahum
AU - Meijerink, Martijn R.
JO - Dentomaxillofacial Radiology
PY - 2021
VL - 301
TODO - 3
SP - 533--540
PB - 
SN - null
TODO - 10.1148/radiol.2021203715
TODO - Humans, Reproducibility of Results, Consensus, Societies, Medical, Ablation Techniques/*methods, Neoplasms/*surgery
TODO - There is currently no consensus regarding preferred clinical outcome measures following image-guided tumor ablation or clear definitions of oncologic end points.  This consensus document proposes standardized definitions for a broad range of  oncologic outcome measures with recommendations on how to uniformly document,  analyze, and report outcomes. The initiative was coordinated by the Society of  Interventional Oncology in collaboration with the Definition for the Assessment of  Time-to-Event End Points in Cancer Trials, or DATECAN, group. According to  predefined criteria, based on experience with clinical trials, an international  panel of 62 experts convened. Recommendations were developed using the validated  three-step modified Delphi consensus method. Consensus was reached on when to assess  outcomes per patient, per session, or per tumor; on starting and ending time and  survival time definitions; and on time-to-event end points. Although no consensus  was reached on the preferred classification system to report complications, quality  of life, and health economics issues, the panel did agree on using the most recent  version of a validated patient-reported outcome questionnaire. This article provides  a framework of key opinion leader recommendations with the intent to facilitate a  clear interpretation of results and standardize worldwide communication. Widespread  adoption will improve reproducibility, allow for accurate comparisons, and avoid  misinterpretations in the field of interventional oncology research. Published under  a CC BY 4.0 license. Online supplemental material is available for this article. See  also the editorial by Liddell in this issue.
ER -