TY - JOUR
TI - Influenza virus vaccine in B-cell chronic lymphocytic leukaemia patients.
AU - Gribabis, D. A.
AU - Panayiotidis, P.
AU - Boussiotis, V. A.
AU - Hannoun, C.
AU - Pangalis, G. A.
JO - Acta Haematologica
PY - 1994
VL - 91
TODO - 3
SP - 115--118
PB - 
SN - 0001-5792, 1421-9662
TODO - 10.1159/000204315
TODO - Humans, Female, Male, Adult, Vaccination, Aged, Middle Aged, Antibody Formation, Hypersensitivity, Delayed/etiology, Hypersensitivity, Immediate/etiology, Influenza Vaccines/*administration & dosage/adverse effects, Leukemia, Lymphocytic, Chronic, B-Cell/*immunology
TODO - The clinical reaction and the immunological response to influenza virus vaccine were studied in 43 B-cell chronic lymphocytic leukaemia patients. The Vaxigrip vaccine  was administered containing the antigens A/Ghizhou/54/89, A/Singapore/6/86, and  B/Yamagata/16/88. The side-effects observed were minimal and well tolerated.  Antibody production with titres > 1:20 on day 15 was observed at least for one  antigen in 35 patients (81%). In 23 of them (63%) this response was retained on days  30 and 60. Patients with IgG levels (< 700 mg/dl) responded less well as compared to  those having normal IgG levels (> 700 mg/dl).
ER -