TY - JOUR
TI - Stressful life events and psychosocial correlates of pediatric inflammatory bowel disease activity.
AU - Giannakopoulos, George
AU - Chouliaras, George
AU - Margoni, Daphne
AU - Korlou, Sophia
AU - Hantzara, Vassiliki
AU - Panayotou, Ioanna
AU - Roma, Eleftheria
AU - Liakopoulou, Magda
AU - Anagnostopoulos, Dimitris C.
JO - World Journal of Biological Psychiatry
PY - 2016
VL - 6
TODO - 3
SP - 322--328
PB - 
SN - 1562-2975, 1814-1412
TODO - 10.5498/wjp.v6.i3.322
TODO - Anxiety, Depression, Children and adolescents, Inflammatory bowel disease, Stressful events
TODO - AIM: To investigate the association of psychiatric and psychosocial correlates with inflammatory bowel disease (IBD) activity in children and adolescents. METHODS: A  total of 85 pediatric IBD patients (in remission or active state of the disease) and  their parents completed a series of questionnaires and semi-structured interviews  measuring life events, depression, anxiety, family dysfunction, and parent mental  health. Differences between the remission and the IBD active group and the  association of any significant variable with the disease activity state were  examined. RESULTS: Parents of children being in active state of the disease reported  more life events (P = 0.005) and stressful life events (P = 0.048) during the past  year and more mental health symptoms (P < 0.001), while the children themselves  reported higher levels of anxiety symptoms (P = 0.017) compared to the remission  group. In the logistic regression multivariate analysis, the only predictor which  had a significant positive effect on the probability of the patients being in active  state was parent mental health symptoms (OR = 4.8; 95%CI: 1.2-25.8). CONCLUSION:  Life events, child anxiety and parent mental health symptoms may be important  correlates of pediatric IBD activity and targets of thorough assessment and  treatment.
ER -